2018
DOI: 10.1590/1678-5150-pvb-5825
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Abstract: An outbreak of skin burn and ocular damage by calcium oxide in swines is reported. The outbreak occurred in a rural property located in the municipality of Iuiu, Western Bahia, during the transport of 60 pigs from a recreation farm to a fattening farm. The observed macroscopic lesions were erythematous areas; formation of papules, vesicles, and in some cases, there was the formation of firm, parched, high brown plaques and in other cases detachment and loss of skin. His eyes were dull. Histological analysis of… Show more

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Cited by 2 publications
(3 citation statements)
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“…This finding was in contrary to a previous study which demonstrated that no pathological changes were observed in the layers of skin (epidermis, dermis and hypodermis), whereas degenerations, hemorrhages and necrosis were observed in liver, kidney and brain post three months intravenous administration of CaO NPs (11 nm) in rats [25]. In contrast, skin burn was reported in swine after exposure to CaO NPs where an area of necrosis of the epidermis and dermis was observed [24].…”
Section: Discussioncontrasting
confidence: 95%
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“…This finding was in contrary to a previous study which demonstrated that no pathological changes were observed in the layers of skin (epidermis, dermis and hypodermis), whereas degenerations, hemorrhages and necrosis were observed in liver, kidney and brain post three months intravenous administration of CaO NPs (11 nm) in rats [25]. In contrast, skin burn was reported in swine after exposure to CaO NPs where an area of necrosis of the epidermis and dermis was observed [24].…”
Section: Discussioncontrasting
confidence: 95%
“…However, one of the challenges associated with the nanoparticles is that the mucosal tissue interaction still needs to be elucidated. Most of the in vivo studies with CaO-NPs have focused on assessing the impact of these particles on the skin [24], liver, kidney and brain [25] after treatment. Histological analysis of the skin and corneal revealed areas of necrosis [24].…”
Section: Introductionmentioning
confidence: 99%
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