2018
DOI: 10.1590/1678-5150-pvb-5307
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Abstract: RESUMO: A dor pós-operatória em cães que são submetidos a cirurgias da coluna vertebral é considerada severa e seu manejo inadequado pode influenciar no tempo de recuperação do paciente, na qualidade de vida e no resultado cirúrgico. Dentre os analgésicos indicados para uso no pós-operatório dessas cirurgias tem-se os opioides, que podem apresentar inúmeros efeitos adversos que requerem atenção. Devido à escassez de estudos clínicos acerca desse assunto em se tratando do pós-operatório de cães, objetivou-se co… Show more

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Cited by 6 publications
(6 citation statements)
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“…In the study by Ripplinger et al (2018) the main adverse effects in dogs that underwent spinal surgery and who were administered morphine, methadone or tramadol in postoperative analgesia were hypophagia, anorexia, and vomiting. Similar results were found in a prospective study in which methadone was used every four hours or as needed according to the CMPS-SF (Bini et al 2018).…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In the study by Ripplinger et al (2018) the main adverse effects in dogs that underwent spinal surgery and who were administered morphine, methadone or tramadol in postoperative analgesia were hypophagia, anorexia, and vomiting. Similar results were found in a prospective study in which methadone was used every four hours or as needed according to the CMPS-SF (Bini et al 2018).…”
Section: Discussionmentioning
confidence: 99%
“…There is still no consensus on which drug or protocol is the most effective for the postoperative analgesia in dogs undergoing spinal procedures, since both opioids and nonopioids drugs (non-opioid analgesics, NSAIDs, gabapentin, pregabalin, methocarbamol, medetomidine, diazepam, lidocaine) have already been described for this purpose (Forterre et al 2008, Aghighi et al 2012, Barker et al 2013, Taylor-Brown et al 2015, Giudice et al 2017, Re Bravo et al 2018, Ripplinger et al 2018, Schmierer et al 2020.…”
Section: Introductionmentioning
confidence: 99%
“…Based on these findings, tramadol seems appropriate for reducing lumbosacral pain to some degree, but some dogs might fail to respond despite high doses and a shortened dosing time. Ripplinger et al [ 74 ] supported this statement after evaluating 180 dogs undergoing vertebral surgery, where 15% of 46 dogs receiving tramadol (3 to 8 mg/kg SC) revealed a higher percentage of persistent pain than other opioids (morphine and methadone) (15%, 4.8%, and 3.3%, respectively). The authors attributed this finding to pharmacokinetics and suggested that tramadol should not be employed as monotherapy or first-line therapy for long-term orthopedic pain management.…”
Section: Therapeutic Efficacy Of Tramadol In Dogsmentioning
confidence: 96%
“…Several studies have found that dipyrone is effective as an analgesic in postoperative pain in dogs undergoing removal of tumors, ovarian hysterectomy, and splenic torsion (Caulkett et al, 2003;Imagawa et al, 2011;Zanuzzo et al, 2015;Guerrero et al, 2015;Bellio et al, 2015;Souza et al, 2016;Ortiz et al, 2016;Ferrigno et al, 2016;Sembenelli et al, 2016;Dalmolin et al, 2020). For Ripplinger et al (2018), the association of metamizole and morphine or metamizole and methadone did not result in an increase in adverse effects in dogs when compared to animals treated with morphine or methadone alone. On the other hands, an intraoperative study revealed that although all patients developed hypothermia regardless of the anesthetic medication administered, and untreated dogs with metamizole reached normothermia more quickly in the postoperative period (Schidelko-Prandl et al, 2019).…”
Section: Analgesic Effectmentioning
confidence: 99%