2018
DOI: 10.1590/1678-4324-2017160341
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Abstract: Light and scanning electron microscopic studies of erythrocytes of Channa punctata exposed to two sublethal doses of lindane over a period of 21 days revealed myriads of anomalies. High frequency of micronucleus appeared progressively in the erythrocyte, ranging from 3.8-7.5%, when monitored weekly for 21 d at 0.25 g/L and 1.0-3.0% at 0.025 g/L lindane. Prominent structural anomalies of erythrocytes included abnormal shapes, vacuolation, membrane invagination and disintegration. At higher dose and at later dur… Show more

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“…Changes in erythrocyte cell and nuclear morphology are related to disorders that affect homeostasis (Tavares-Dias & Moraes 2004), including excess free radicals (Cimen 2008) and temperature variations (Qiang et al 2013, de Pedro et al 2005. Although the erythrocyte morphological changes are widely used to indicate environmental genotoxicity (Bhattacharjee & Das 2017, Maheshwari & Dua 2016, Grisolia et al 2009, this methodology was pointed out as an efficient tool in the biomonitoring of thermal stress in notothenids (Zafalon-Silva et al 2017). And this study attempted to ensure the quality and control of the experimental conditions, for both the animals submitted to the increased temperature (8°C) and control animals (0°C).…”
Section: Discussionmentioning
confidence: 99%
“…Changes in erythrocyte cell and nuclear morphology are related to disorders that affect homeostasis (Tavares-Dias & Moraes 2004), including excess free radicals (Cimen 2008) and temperature variations (Qiang et al 2013, de Pedro et al 2005. Although the erythrocyte morphological changes are widely used to indicate environmental genotoxicity (Bhattacharjee & Das 2017, Maheshwari & Dua 2016, Grisolia et al 2009, this methodology was pointed out as an efficient tool in the biomonitoring of thermal stress in notothenids (Zafalon-Silva et al 2017). And this study attempted to ensure the quality and control of the experimental conditions, for both the animals submitted to the increased temperature (8°C) and control animals (0°C).…”
Section: Discussionmentioning
confidence: 99%