2017
DOI: 10.1590/1678-4162-9190
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Abstract: Meningoencephalitis caused by Bovine herpesvirus 5 (BoHV-5) is an important neurological disease that affects Brazilian cattle herds. The present study investigated the presence of BoHV-5 DNA in cattle diagnosed with meningoencephalitis at Faculdade de Medicina Veterinária e Zootecnia, UNESP -Univ Estadual Paulista from 1980 to 2009. The records obtained from the Large Animal Internal Medicine Service and the Animal Pathology Service were reviewed to identify clinical and epidemiological data from cattle with … Show more

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Cited by 2 publications
(3 citation statements)
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“…More than 70% of individuals (104 cases) affected by NME were 12-to 24-month-old cattle. NME by BoHV-5 is typically described in the literature as a disease of young calves (Colodel et al 2002, Elias et al 2004, Halfen & Riet-Correa 2007, Galiza et al 2010, Cagnini et al 2017, Middleton 2017; however, some reports indicate that the disease can occur in adult cattle (Roels et al 2000, Rissi & Barros 2013. Morbidity was up to 11%.…”
Section: Discussionmentioning
confidence: 99%
“…More than 70% of individuals (104 cases) affected by NME were 12-to 24-month-old cattle. NME by BoHV-5 is typically described in the literature as a disease of young calves (Colodel et al 2002, Elias et al 2004, Halfen & Riet-Correa 2007, Galiza et al 2010, Cagnini et al 2017, Middleton 2017; however, some reports indicate that the disease can occur in adult cattle (Roels et al 2000, Rissi & Barros 2013. Morbidity was up to 11%.…”
Section: Discussionmentioning
confidence: 99%
“…The effect of the oxoquinolines 4a-k on viral replication was evaluated at various time intervals up to 72 h, in accordance with procedures previously described [32] modified by Pinto et al [28]. MDBK cells were grown in 24-well culture plates at a density of 2x10 4 cells per well. After 24 h MDBK monolayers were pretreated with oxoquinolines (4h = 25 μM; 4j = 25 μM; 4k = 25 μM) and four times the EC 50 value of ACV = 664 μM for 1 h. MDBK cells without pretreatment were mock-infected or inoculated with BoHV-5RJ42/01 (200 PFU) and incubated for 1 h at 37°C with a 5% CO 2 atmosphere for virus adsorption.…”
Section: Methodsmentioning
confidence: 99%
“…Bovine herpes viruses type 5 (BoHV-5) is an enveloped double-stranded DNA virus, belonging to the genus Varicellovirus , subfamily Alphaherpesvirinae , family Herpesviridae [1,2]. These considerations lead us to suggest it can be the aetiologic agent of neurological disease, associated to fatal meningoencephalitis in cattle, which compromises their productivity and makes the slaughter for meat consumption impossible [3,4]. This viral infection has been reported in Australia [5], United States [6], Europe [7], Argentina [8] and Brazil [9,10], affecting mainly but not exclusively young animals.…”
Section: Introductionmentioning
confidence: 99%