Sensitization study of dogs with atopic dermatitis in the central region of Rio Grande do Sul

Abstract

Canine atopic dermatitis (CAD) is a common dermatosis, defined as a genetic-related disease which predisposes to skin inflammation and pruritus, associated to a IgE-specific response in most of cases. Clinical diagnosis may be later complemented by skin allergy and/or serological tests. The aim of these tests is to identify possible allergens in order to enable the clinicians to select candidate antigens for allergen specific immunotherapy. In the present study 58 CAD positive animals were tested. All were submitted to the intradermal test (IDT) and screened for the presence of antibodies against different antigens using ELISA. The obtained results show a high prevalence of sensitization among the tested dogs to house dust mites and to pollen of C. dactylon. With this work it was possible to identify the main allergens involved in immunological response of dogs with CAD living in central area of Rio Grande do Sul.

Grass pollen sensitization in dogs in Paraná, Brazil: comparison between percutaneous and intradermal testing

“…Sensitization to CD was detected in 16.8 and 80% of patients with rhinitis in Curitiba (Araújo et al, 2015) and Rio Grande do Sul (Vieira et al., 2011), respectively. A previous study using IDT in Brazil found that 24.13% of atopic dogs were sensitized to CD (Pereira et al, 2015). In the present study, the positive response to this grass was similar to the other studies cited.…”

“…In dogs, the prevalence of grass pollen sensitization ranges from 10 to 27.7% (Masuda et al, 2000;Roussel et al, 2013). In Brazil, one study using IDT identified 10.3% of sensitization in atopic dogs using grass polens extracts (Pereira et al, 2015). In the present study using PT, the prevalence of sensitization to grass pollen was (25.6%) and CD and LM were the most important species.…”

“…Females in estrus, gestation or lactation and dogs with chronic systemic diseases or with any other dermatopathy were also not included. All dogs in this study were submitted to the IDT and PT sequentially in the same day by the same examinator, who previously did a proficiency test as described by Cunha et al (2015).…”

“…Veterinary studies to verify the incidence of pollinosis in Brazil are rare. A recent study that used intradermal skin test (IDT) in 58 dogs with atopic dermatitis in Rio Grande do Sul state, demonstrated a positive response to CD (24.13%), and PN (12%) (Pereira et al, 2015). Sensitization to LM was not evaluated.…”

A randomised, double‐blinded trial to assess the effect of oclacitinib and prednisolone on intradermal allergen and prick tests in dogs with atopic dermatitis

“…Therefore, the aim of the present study was to evaluate the influence of oclacitinib and prednisolone on IDT and PT immediate-phase reactions in dogs diagnosed with atopic dermatitis, sensitised to environmental allergens commonly involved as inciting allergens in Brazil. [18][19][20]…”