Evaluation of coronary dominance in pigs; a comparative study with findings in human hearts

Gómez, Fabián A.; Ballesteros, Luis Ernesto

doi:10.1590/1678-4162-6637

Cited by 8 publications

(6 citation statements)

References 11 publications

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“…In contrast, in pigs and horses, the SIB originates primarily from the RCA [14,23,25,54,62]. According to reports, in pigs, the percentages of left dominant, right dominant and balanced types are 0 to 15%, 67 to 100% and 0 to 33%, respectively [14,23,54,62]. In humans, the percentages of left dominant, right dominant, and balanced hearts varies between 7 to 20%, 48 to 72%, and 0 to 34%, respectively [1,29,33,42,47,56].…”

Section: Discussionmentioning

confidence: 97%

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Prevalence of anatomic variants in coronary arteries of Japanese Black cattle

Ohashi

Wakitani

Yasuda

2023

The Journal of Veterinary Medical Science

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Coronary artery anomalies that can cause sudden cardiac death have been described in some mammals. However, few studies have investigated coronary anomalies and coronary artery branching patterns in cattle. Therefore, understanding of bovine coronary arteries is incomplete. The aim of this study was to clarify anatomic variants in coronary arteries of Japanese Black cattle. The gross anatomy of the coronary arteries was examined in the hearts of 100 cattle. A total of 14 of 100 hearts exhibited confirmed coronary anomalies in the left main trunk. These 14 hearts were classified into 5 types potentially associated with cardiac ischemia. Regarding the coronary branches, the subsinuosal interventricular branch originated from the left circumflex branch (LCX) in 98 hearts and from the right coronary artery in 2 hearts. The origin of the sinoatrial nodal branch was classified into 3 types. In 99 hearts, the atrioventricular nodal branch originated from the LCX at the heart crux. This study characterized the prevalence of coronary anomalies, branching patterns of coronary arteries, and coronary artery anatomic variants in Japanese Black cattle.

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Section: Discussionmentioning

confidence: 97%

“…In dogs, the SIB originates primarily from the LCX [46,50]. In contrast, in pigs and horses, the SIB originates primarily from the RCA [14,23,25,54,62]. According to reports, in pigs, the percentages of left dominant, right dominant and balanced types are 0 to 15%, 67 to 100% and 0 to 33%, respectively [14,23,54,62].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of anatomic variants in coronary arteries of Japanese Black cattle

Ohashi

Wakitani

Yasuda

2023

The Journal of Veterinary Medical Science

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“…34 As with their human counterparts however, certain inter-species variants are present, and should be kept in mind whilst choosing a porcine animal model. 34,35 With regards to the coronary arterial system, in contrast to their porcine and human analogues, ovine species primarily have a left coronary type circulation; ergo, the majority of the myocardium receives its blood supply via branches of the left coronary artery. 36 However, given that ovines do not possess an extensive coronary collateral network, it may be still suitable to utilise their models for research.…”

Section: Coronary Anatomymentioning

confidence: 99%

Comparative review of large animal models for suitability of proximal aortic endovascular repair

2022

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Background The advent of TEVAR heralds a paradigm shift in treating descending aortopathies and is viewed as a potential option for ascending aortic dissection (AD) repair too. Currently, TEVAR’s usage for ascending aortopathies remains limited. Consequently, an urgent requirement exists to choose appropriate animal models to better contemporary understanding of endovascularly treating Type-A ADs. This review article provides a summary of current literature on this topic. Two broad sections are covered, including the macroscopic differences between adult swine, ovine and porcine species versus that of their human counterparts, as well as the valvular, aortic and coronary vasculature variances. Methods A narrative review was conducted to integrate current findings of anatomical differences in valvular and ascending aortic anatomy amongst the aforementioned species. An electronic search of PubMed and Ovid Medline databases from January 1965 to June 2020 was performed, limited to articles published in English. Results Whilst macroscopic anatomy remains grossly similar, differences in valvular leaflet shape are present, with swine and porcine models possessing anatomic characteristics that are comparable to their human counterparts. Research into inter-species ascending aortic anatomy has not been extensively performed, highlighting a literature gap. Conversely, multiple morphological studies have highlighted that swine coronary vasculature is closely resemblant to that of man. Conclusion Both swine and ovine species are suitable as appropriate animal models in examining the feasibility of endovascular stent-grafts for ascending ADs. However, given the similarities in coronary and aortic valve anatomy to their human analogues, porcine models are better suited for this purpose.

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“…The heart of a domestic swine is similar to that of a Human, not only in terms of size, anatomy, distribution of blood perfusion, and cardiovascular physiology (HUGHES, 1986), but also in terms of the distribution of arteries BALLESTEROS, 2013BALLESTEROS, , 2014BALLESTEROS, , 2015.…”

Section: Introductionmentioning

confidence: 99%

Origin and distribution of the coronary arteries of boars

Borges¹,

Ribeiro²,

Romão³

et al. 2019

Braz. J. Vet. Res. Anim. Sci.

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The heart of a domestic swine is similar to that of a human regarding anatomy, blood perfusion, and distribution of nurturing arteries. In addition to the similarities, its low cost compared with other species is also one of the reasons these animals have been increasingly used in medical schools and in clinical, surgical, and pharmacological studies. Therefore, we aimed to identify the origin and distribution of the right and left coronary arteries of boars, emphasizing the configuration and macroscopic representativity of their branches while characterizing a possible dominance concerning the type of circulation and the potential use of this animal as an experimental model, hence boars are the ancestors of the domestic pigs. The left coronary artery has bifurcated into paraconal interventricular branch and circumflex branch; or it has trifurcated into paraconal interventricular branch, the oblique branch, and into the left circumflex branch. The right coronary artery has originated the marginal branches to the right ventricle and the right circumflex branch, which has branched out in the subsinuous interventricular branch. Anastomoses have stood out among the paraconal and subsinuous interventricular branches – where a right dominant coronary artery occurred – and between the right and left circumflex branches. We concluded that the morphology and the distribution of the coronary arteries of boars resemble those of a human and, thus, our results are useful for the conception of experimental hemodynamics and possible use as process models.

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Evaluation of coronary dominance in pigs; a comparative study with findings in human hearts

Cited by 8 publications

References 11 publications

Prevalence of anatomic variants in coronary arteries of Japanese Black cattle

Prevalence of anatomic variants in coronary arteries of Japanese Black cattle

Comparative review of large animal models for suitability of proximal aortic endovascular repair

Origin and distribution of the coronary arteries of boars

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