Outcomes of segmental femoral artery pseudoaneurysm in patients with Behçet’s disease: a single center’s experience

Khairy, Hussein; Shaker, Ahmed

doi:10.1590/1677-5449.180139

Cited by 3 publications

(1 citation statement)

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“…Pathergy, arterial occlusion, arterial stenosis, and arterial thrombosis are risk factors for aneurysm formation ( 35 ). The incidence of pseudoaneurysms is higher than that of true aneurysms in BD patients, and pseudoaneurysms are more likely to rupture ( 36 ), the formation of which is related to traumatic artery operation ( 37 ). The relapse rate of vascular involvement was 23% at 2 years and 38.4% at 5 years ( 38 ).…”

Section: Discussionmentioning

confidence: 99%

Case report and analysis: Behçet’s disease with lower extremity vein thrombosis and pseudoaneurysm

Wang

Zhang

et al. 2022

Front. Immunol.

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BackgroundBehçet’s disease (BD) is a unique autoimmune chronic systemic vasculitis that affects veins and arteries of all sizes. BD can lead to recurrent vascular events, especially venous thrombosis, with an incidence rate of 40%, or pseudoaneurysms formed under long-term inflammatory reaction or iatrogenic stimulation. BD-related risk factors promote endothelial dysfunction, platelet activation and overactivation of tissue factors leading to mural inflammatory thrombi. Thrombosis may be the first clinical manifestation of BD.Case presentationA 32-year-old man complaining of progressive swelling and pain in the right lower extremity for 30 days was initially diagnosed with “venous thrombosis of the right lower extremity,” using color Doppler ultrasonography. Patient underwent inferior vena cava filter placement combined with deep vein angioplasty of the right lower extremity and catheter-directed urokinase thrombolysis. Postoperative oral anticoagulant therapy was administered. However, the patient was readmitted 20 days later for pulsatile pain in the right groin. Prior medical history included 4 years of repeated oral and perineal ulcers, and 2 months of blurred vision. Abdominal computed tomography angiography (CTA) revealed rupture of the right common iliac artery (CIA) and left internal iliac artery (IIA), complicated by a pseudoaneurysm. Based on the clinical manifestations and other auxiliary examination results, the patient was re-diagnosed with “BD combined with deep venous thrombosis of the right lower extremity and an iliac artery pseudoaneurysm.” Stent implantation was performed for iliac artery pseudoaneurysm after symptoms were controlled with timely immunosuppressive therapy. After endovascular treatment, the patient underwent continued immunosuppressive therapy and dynamic reexaminations of abdominal CTA, which revealed that a small amount of contrast agent at the stent in the right CIA continued to flow into the cavity of the pseudoaneurysm; in addition, the size of the pseudoaneurysm was gradually increasing. Therefore, the patient underwent a second stent implantation for iliac artery pseudoaneurysm, and the condition improved further.ConclusionThe importance of early diagnosis of BD should be recognized, and the choice of interventional and surgical procedures should be carefully evaluated, as this may trigger further damage to vascular access in BD patients with aneurysm.

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