2020
DOI: 10.1590/1519-6984.216607
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Abstract: Schistosomiasis treatment is dependent on a single drug, praziquantel (PZQ). The development of resistance of PZQ has drawn the attention of many researchers to alternative drugs. One viable and promising treatment is the study of medicinal plants as a new approach to the experimental treatment for Schistosomiasis. The present work aimed to evaluate in vivo antischistosomal activity of effect of Mentha x villosa Oil Essential (Mv-EO) and rotundifolone (ROT) against Schistosoma mansoni. Thirty-day-old female Sw… Show more

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Cited by 4 publications
(2 citation statements)
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“…One of such studies showed that mice infected with 80 cercariae and orally treated with the EO from Mentha × villosa at dose 200 mg kg À 1 and its main compound, rotundifolone, at a dose of 141.9 mg kg À 1 , 45 days post-infection for five consecutive days have significantly reduced worm burden (72.44 % and 74.48 %, respectively) and the number of eggs obtained from liver, intestinal and fecal samples. [33] The EO from Melaleuca armillaris, orally administrated at 150 mg kg À 1 for two successive days eight weeks post-infection, improves the disturbing levels of GSH (glutathione) and MDA (malondialdehyde) in infected mice. In addition, the levels of vitamins C and E increase and the liver and body weights in infected mice are improved as compared to the infected-untreated group.…”
Section: Introductionmentioning
confidence: 99%
“…One of such studies showed that mice infected with 80 cercariae and orally treated with the EO from Mentha × villosa at dose 200 mg kg À 1 and its main compound, rotundifolone, at a dose of 141.9 mg kg À 1 , 45 days post-infection for five consecutive days have significantly reduced worm burden (72.44 % and 74.48 %, respectively) and the number of eggs obtained from liver, intestinal and fecal samples. [33] The EO from Melaleuca armillaris, orally administrated at 150 mg kg À 1 for two successive days eight weeks post-infection, improves the disturbing levels of GSH (glutathione) and MDA (malondialdehyde) in infected mice. In addition, the levels of vitamins C and E increase and the liver and body weights in infected mice are improved as compared to the infected-untreated group.…”
Section: Introductionmentioning
confidence: 99%
“…O óleo essencial das folhas de hortelã apresenta potencial larvicida do mosquito da dengue (Aedes aegypti L.) (LIMA et al, 2006) e contribui nas funções cardíacas (MATOS-ROCHA et al, 2020). O uso das folhas também apresenta propriedades antiparasitárias (FONSECA et al, 2020), e o extrato hidroalcólico foi eficaz para o controle da fase juvenil de nematoides gastrintestinais de bovinos por meio de teste in vitro (NASCIMENTO et al, 2009).…”
Section: Introductionunclassified