Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America

Carta, Mauro Giovanni; Moro, Maria Francesca; Piras, Martina; Ledda, Vanessa; Prina, Eleonora; Stocchino, Serena; Orrù, Germano; Romano, Ferdinando; Brasesco, María Verónica; Freire, Rafael C.; Nardi, Antônio Egídio; Tondo, Leonardo

doi:10.1590/1516-4446-2018-0338

Cited by 7 publications

(2 citation statements)

References 23 publications

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“…However, this may well be due to a greater diagnosis of Bipolar Spectrum Disorders rather than appreciably increased prevalence rates. Having said this, increasing urbanization seen in recent years also appears to increase the prevalence of psychiatric disorders including BD [84][85][86][87]. This is a concern with a positive relationship seen between increasing urbanization and increasing number of suicides [88].…”

Section: Bipolar Disorders (Bd) Including Prevalence and Burden Of Ilmentioning

confidence: 98%

Pharmacotherapeutic interventions for bipolar disorder type II: addressing multiple symptoms and approaches with a particular emphasis on strategies in lower and middle-income countries

Godman

Grobler

Van-De-Lisle

et al. 2019

Expert Opinion on Pharmacotherapy

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Introduction: Appropriately managing mental disorders is a growing priority across countries in view of the impact on morbidity and mortality. This includes patients with bipolar disorders (BD). Management of BD is a concern as this is a complex disease with often misdiagnosis, which is a major issue in lower and middleincome countries (LMICs) with typically a limited number of trained personnel and resources. This needs to be addressed. Areas covered: Medicines are the cornerstone of managing patients with Bipolar II across countries including LMICs. The choice of medicines, especially antipsychotics, is important in LMICs with high rates of diabetes and HIV. However, care is currently compromised in LMICs by issues such as the stigma, cultural beliefs, a limited number of trained professionals and high patient co-payments. Expert opinion: Encouragingly, some LMICs have introduced guidelines for patients with BD; however, this is very variable. Strategies for the future include addressing the lack of national guidelines for patients with BD, improving resources for mental disorders including personnel, improving medicine availability and patients' rights, and monitoring prescribing against agreed guidelines. A number of strategies have been identified to improve the treatment of patients with Bipolar II in LMICs, and will be followed up.

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Section: Bipolar Disorders (Bd) Including Prevalence and Burden Of Ilmentioning

confidence: 98%

Pharmacotherapeutic interventions for bipolar disorder type II: addressing multiple symptoms and approaches with a particular emphasis on strategies in lower and middle-income countries

Godman

Grobler

Van-De-Lisle

et al. 2019

Expert Opinion on Pharmacotherapy

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show abstract

“…Most studies on the HCL - 32 and the MDQ have been carried out in Western countries. The epidemiology of BD shows minor variations by country and ethnicity [ 26 , 27 ], and the disorder has a likely genetic basis rooted in evolutionary mechanisms [ 28 , 29 ]. However, cultural factors may influence how symptoms leading to the diagnosis of BD are evaluated [ 26 , 30 ].…”

Section: Introductionmentioning

confidence: 99%

Accuracy of the Arabic HCL - 32 and MDQ in detecting patients with bipolar disorder

et al. 2023

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Background Studies about the two most used and validated instruments for the early detection of Bipolar Disorder (BD), the 32 - item Hypomania Checklist (HCL - 32) and the Mood Disorder Questionnaire (MDQ), are scarce in non-Western countries. This study aimed to explore the reliability, factor structure, and criterion validity of their Arabic versions in a sample of Tunisian patients diagnosed with mood disorders. Methods The sample included 59 patients with BD, 86 with unipolar Major Depressive Disorder (MDD) and 281 controls. Confirmatory factor analysis was applied to show that a single global score was an appropriate summary measure of the screeners in the sample. Receiver Operating Characteristic analysis was used to assess the capacity of the translated screeners to distinguish patients with BD from those with MDD and controls. Results Reliability was good for both tools in all samples. The bifactor implementation of the most reported two-factor model had the best fit for both screeners. Both were able to distinguish patients diagnosed with BD from putatively healthy controls, and equally able to distinguish patients diagnosed with BD from patients with MDD. Conclusion Both screeners work best in excluding the presence of BD in patients with MDD, which is an advantage in deciding whether or not to prescribe an antidepressant.

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Specific cultural factors are associated with the incidence and burden of bipolar disorder: An ecological analysis of data from 115 countries

Rajkumar

2021

Journal of Affective Disorders Reports

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Megacities, migration and an evolutionary approach to bipolar disorder: a study of Sardinian immigrants in Latin America

Cited by 7 publications

References 23 publications

Pharmacotherapeutic interventions for bipolar disorder type II: addressing multiple symptoms and approaches with a particular emphasis on strategies in lower and middle-income countries

Pharmacotherapeutic interventions for bipolar disorder type II: addressing multiple symptoms and approaches with a particular emphasis on strategies in lower and middle-income countries

Accuracy of the Arabic HCL - 32 and MDQ in detecting patients with bipolar disorder

Specific cultural factors are associated with the incidence and burden of bipolar disorder: An ecological analysis of data from 115 countries

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