Body self-image disturbances in women with prolactinoma

Pereira, Helen S; Naliato, Erika Cesar de Oliveira; Moraes, Aline Barbosa; Gadelha, Mônica R.; Neto, Leonardo Vieira; Almeida, R. M. V. R.; Nardi, Antônio Egídio; Violante, A

doi:10.1590/1516-4446-2018-0325

Cited by 3 publications

(3 citation statements)

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“…About half of the women reported still having hyperprolactinemia related symptoms after treatment and those women reported higher incidence of body dissatisfaction than women without symptoms. They also found that distorted self-image was more common in the group of women without symptoms related to hyperprolactinemia 35 . In our study, all women were untreated, and we did not measure body dissatisfaction in the same way as Pereira et al did.…”

Section: Discussionmentioning

confidence: 95%

“…One important finding in our study was that physical symptoms related to bodily changes were reported by more than half of the women. In a study by Pereira et al [35] body dissatisfaction and a distorted body self-image were evaluated in 80 women with either surgery or medical treated prolactinoma. About half of the women reported still having hyperprolactinemia related symptoms after treatment and those women reported higher incidence of body dissatisfaction than women without symptoms.…”

Section: Discussionmentioning

confidence: 99%

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Reduced Health Related Quality of Life, Increased Fatigue, and Daytime Sleepiness in Women with Hyperprolactinemia

et al. 2023

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Prolactin has many physiological effects and seems to be involved in the human quality of life and well-being. The aim of this study was to describe health related quality of life, fatigue and daytime sleepiness in women with untreated hyperprolactinemia. In total 32 women (mean age 37.0 ± 10.9) with verified hyperprolactinemia completed a questionnaire including questions on fatigue, measured with the Swedish version of the Fatigue Impact Scale (FIS), propensity to fall in sleep, measured with the Swedish version of the Epworth Sleepiness Scale (ESS), and Health related quality of life (HRQoL), measured by the Short-Form-36 scale (SF-36). For comparison Swedish normative data were used. The women were also interviewed regarding different symptoms related to hyperprolactinemia and the answers were analyzed using qualitative content analysis. HRQoL, as measured with SF-36, was significantly lower in all dimensions, except in physical function, compared to the Swedish reference population. Total FIS was 54.3 (41.1) and mean score on the ESS was 8.7 (4.2) indicating increased fatigue and deterioration in night sleep. The women felt very tired, and several of them rarely felt rested in the morning. The restless night sleep and the fatigue during the daytime got them to feel feeble and sometimes to find it difficult to concentrate, which affected both their mood and life in general. Women diagnosed with hyperprolactinemia reported deterioration in night sleep, increased rate of fatigue, and a reduced health related quality of life in comparison with the reference population.

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Section: Discussionmentioning

confidence: 95%

Section: Discussionmentioning

confidence: 99%

Reduced Health Related Quality of Life, Increased Fatigue, and Daytime Sleepiness in Women with Hyperprolactinemia

et al. 2023

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“…However, the relationships between PRL and anxiety and depression in prolactinoma patients remain to be explored. It has been reported that prolactinoma patients may experience dissatisfaction with their body image due to weight gain, and symptomatic patients have a higher rate of body dissatisfaction than asymptomatic patients ( 4 ). Prolactinoma patients often exhibit symptoms of depression, hostility, irritability, and anxiety ( 5 , 6 ), and stress may trigger neuroendocrine changes involving dopamine or serotonin, thus affecting the release of PRL ( 7 ).…”

Section: Introductionmentioning

confidence: 99%

A study on the correlations of PRL levels with anxiety, depression, sleep, and self-efficacy in patients with prolactinoma

Miao,

Fu,

Luo

et al. 2024

Front. Endocrinol.

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PurposeThe purpose of this study was to explore the factors influencing PRL levels in patients with prolactinoma and to investigate the correlations between anxiety, depression, sleep, self-efficacy, and PRL levels.MethodsThis retrospective study included 176 patients with prolactinoma who received outpatient treatment at the Affiliated Hospital of Zunyi Medical University from May 2017 to August 2022. The general information questionnaire, Hospital Anxiety and Depression Scale (HADS), Athens Insomnia Scale (AIS), and General Self-Efficacy Scale (GSES) were used for data collection. A generalized estimating equation (GEE) model was used to analyze the factors influencing PRL levels in patients with prolactinoma. GEE single-effect analysis was used to compare PRL levels at different time points between anxiety group and nonanxiety group, between insomnia group and normal group, and between low, medium, and high self-efficacy groups.ResultsThe median baseline PRL level and the PRL levels at 1, 3, 6, and 12 months of follow-up were 268.50 ng/ml, 122.25 ng/ml, 21.20 ng/ml, 19.65 ng/ml, and 16.10 ng/ml, respectively. Among patients with prolactinoma, 59.10% had anxiety (HADS-A score = 7.35 ± 3.34) and 28.98% had depression (HADS-D score = 5.23 ± 3.87), 9.10% had sleep disorders (AIS score = 6.10 ± 4.31) and 54.55% had low self-efficacy (GSES score = 2.13 ± 0.83). Educational level, tumor size, number of visits, sleep quality, anxiety level, and self-efficacy level were found to be factors influencing PRL levels in patients with prolactinoma (P<0.05). Higher PRL levels were observed in the anxiety group compared to the non-anxiety group (P<0.001), in the insomnia group compared to the normal group (P<0.05), and in the low self-efficacy group compared to the medium and high self-efficacy groups (P<0.05).ConclusionPRL levels in patients with prolactinoma are related to education level, tumor size, number of visits, anxiety, self-efficacy, and sleep but not depression. PRL levels were higher in patients with anxiety, low self-efficacy, and sleep disorders.

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Os Benefícios Do Tratamento De Prolactinoma Em Mulheres Em Idade Fértil

Souza¹,

Souza²,

Feitosa³

et al. 2022

RIS

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INTRODUÇÃO: A presente pesquisa se propõe a análise dos benefícios do tratamento do prolactinoma em mulheres em idade fértil. Os prolactinomas constituem importantes causas de infertilidade e hipogonadismo, constituem as causas de mais de 40% dos adenomas hipofisários e afetam principalmente mulheres jovens e em faixa etária de fertilidade, podendo também acontecer até a sexta década de vida. OBJETIVOS: Foi analisar os benefícios do tratamento de prolactinoma em mulheres em idade fértil. METODOLOGIA: Trata-se de uma revisão da literatura. A busca bibliográfica ocorrerá entre os meses de janeiroa a outubro de 2022, através da Biblioteca Virtual em Saúde (BVS), nas bases de dados Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e Scientific Electronic Library Online (SciELO). Os critérios de inclusão consistirão em artigos publicados nos últimos dez anos, disponíveis na íntegra e acesso gratuito, em idioma português, que abordassem o objetivo da pesquisa. RESULTADOS E DISCUSSÕES: Conforme a literatura um dos maiores benefícios da correção da hiperprolactinemia em mulheres com prolactinoma é a restauração da fertilidade e a possibilidade de engravidar, o que ocorre em cerca de 80% dos casos. CONCLUSÃO: A síntese dos estudos conclui que a prolactina participa da regulação do eixo hipotálamo-hipófise-gônada. Hiperprolactinemia é uma causa bem estabelecida de amenorreia e infertilidade. Nesse contexto, é nítido a necessidade de se realizar mais estudos que busquem conhecimento dos benefícios do tratamento de prolactinoma em mulheres em idade fértil. PALAVRAS-CHAVE: Prolactinoma. Mulheres. Tratamento. Adenoma hipofisário. Agonista dopaminérgico.

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Body self-image disturbances in women with prolactinoma

Cited by 3 publications

References 40 publications

Reduced Health Related Quality of Life, Increased Fatigue, and Daytime Sleepiness in Women with Hyperprolactinemia

Reduced Health Related Quality of Life, Increased Fatigue, and Daytime Sleepiness in Women with Hyperprolactinemia

A study on the correlations of PRL levels with anxiety, depression, sleep, and self-efficacy in patients with prolactinoma

Os Benefícios Do Tratamento De Prolactinoma Em Mulheres Em Idade Fértil

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