False positivity of Rose Bengal test in patients with COVID-19: case series, uncontrolled longitudinal study

Gemcioğlu, Emin; Erden, Abdülsamet; Karabuga, Berkan; Davutoğlu, Mehmet; Ateş, İhsan; Küçükşahin, Orhan; Güner, Rahmet

doi:10.1590/1516-3180.2020.0484.03092020

Cited by 3 publications

(9 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thoracic CT imaging in our patient showed no symptoms of pulmonary brucellosis or other pulmonary disorders such as pneumonia and abscess of lung empyema that are common in endemic countries such as Iran 1,6,9 . Other clinical studies showed that in patients with mild‐to‐moderate COVID‐19 a shared variety of clinical and laboratory features can be found in other diseases including Dengue and Malta fever 3,6 . Other pathogens including influenza, legionnaire illness, dengue virus, and mycoplasma pneumonia are infections widely happening with SARS‐CoV‐2 infection 5,10–13 .…”

Section: Discussionmentioning

confidence: 54%

“…Typical symptoms of brucellosis including fever, malaise, and arthralgia can be similar to COVID‐19 symptoms. The common laboratory findings of these infections are thrombocytopenia and leukopenia 3,7 . In this article, a suspected COVID‐19 case was hospitalized then who was finally diagnosed with co‐infection with brucellosis and discussed.…”

Section: Introductionmentioning

confidence: 98%

“…The co‐infection of COID‐19 with other endemic and local pathogens could detain the suitable medicine of the causative agent 4 . Brucellosis is an endemic zoonosis disease and an important public health issue in most developing countries such as Iran 3,6 . Consumption of raw milk, unpasteurized dairy products, and inhalation of infected droplets can lead to brucellosis 7 .…”

Section: Introductionmentioning

confidence: 99%

“…In the meanwhile, viruses have caused significant problems that have remained hazardous outbreaks 1 . The pandemic of coronavirus disease 2019 (COVID‐19) caused by severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) with a quickly universal spread 2,3 . SARS‐CoV‐2 can involve multiple organs of the body such as respiratory, gastrointestinal, skeletomuscular, and neurologic systems 4 .…”

Section: Introductionmentioning

confidence: 99%

“…1 The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) with a quickly universal spread. 2,3 SARS-CoV-2 can involve multiple organs of the body such as respiratory, gastrointestinal, skeletomuscular, and neurologic systems. 4 Severe diseases arose only in 14% of patients especially in persons with comorbidities including higher age, hypertension, diabetes mellitus, and obesity, cardiac and chronic respiratory diseases.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

COVID‐19 co‐infection in a patient with brucellosis

Shabani

Ghadimi

2022

Clinical Case Reports

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 54%

Section: Introductionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

COVID‐19 co‐infection in a patient with brucellosis

Shabani

Ghadimi

2022

Clinical Case Reports

View full text Add to dashboard Cite

show abstract

False Positive Rose Bengal Test in COVID-19 Patients with Abnormal T3 And T4 Levels

Jasim

2023

View full text Add to dashboard Cite

Brucellosis is a zoonotic infection that is quite frequent. Fever, weakness, sweating, especially at night, and joint discomfort are indications of brucellosis. COVID-19 symptoms are similar to those of brucellosis, which may cause a delay in identifying the latter. Objectives: The study aims to investigate patients with COVID-19 who test positive for Rose Bengal and who suffer from high fever, persistent joint pain, and fatigue, as well as abnormal levels of T4 and T3 hormone determination. 19 was detected in 90 patients (45 males and 45 females) between July 1 and September 20, 2020. The patients' ages ranged from 20 to 63 years. Laboratory tests were 2019-nCoV IgG/IgM COMBO test card, T4, T3, Rose Bengal Plate Test, C-reactive protein test (CRP), and total white blood cell count (WBCs). COVID-19 was detected in 90 patients (45 males and 45 females) between July 1 and September 20, 2020. All patients suffered from fewer white blood cells (less than 4000 cells\ cm3). The level of CRP protein was slightly higher in men than in women during the first week of infection, 40 (88.88%) and 35 (77.77%), respectively. At the same time, the T3 and T4 hormone levels in both sexes were less than expected in most patients. The levels of CRP protein in most patients at the beginning of infection were high (13.7-97 mg/L in both sexes. Five days after contracting COVID-19, a Rose Bengal test was performed on all patients. The highest incidence of brucellosis in COVID-19 patients was in the age groups 21-30 (38.18%) and 31-40 (34.54%), respectively. Doctors worldwide are concentrating on the COVID-19 epidemic. However, they must pay close attention to one crucial point: distinguishing COVID-19 from brucellosis to receive the proper therapy and recover quickly without any drug-related complications. Keywords: COVID-19, brucellosis, Brucella abortus and SARS-CoV-2

show abstract

A case: Rose Bengal test positive Crimean Congo hemorrhagic fever patient

Bozkurt Yavuz

2023

Northwestern Med J

View full text Add to dashboard Cite

Brucella is one of the most common bacterial zoonosis. Crimean-Congo Hemorrhagic Fever (CCHF) is a potentially life-threatening infection. They have similar epidemiologic and clinical presentations. A 40-year-old male patient, engaged in animal husbandry, presented to the emergency unit with complaints of weakness, headache, and fever. Because of his low platelet count, he was referred to the internal medicine clinic. The patient did not have a history of contact with a tick or a CCHF patient. The Brucella Rose Bengal Test (RBT) was performed and the result was positive. After he was referred to the infectious diseases clinic, the CCHF RT-PCR test was found to be positive and the Brucella Wright agglutination test was negative. The patient, who was diagnosed with CCHF, was discharged in good condition. A positive RBT result does not always make a definitive diagnosis of Brucella infection. In areas where CCHF and Brucella are endemic, CCHF should be considered even if there is no history of ticks.

show abstract

False positivity of Rose Bengal test in patients with COVID-19: case series, uncontrolled longitudinal study

Cited by 3 publications

References 11 publications

COVID‐19 co‐infection in a patient with brucellosis

COVID‐19 co‐infection in a patient with brucellosis

False Positive Rose Bengal Test in COVID-19 Patients with Abnormal T3 And T4 Levels

A case: Rose Bengal test positive Crimean Congo hemorrhagic fever patient

Contact Info

Product

Resources

About