The influence of depressive symptoms and substance use on adherence to antiretroviral therapy. A cross-sectional prevalence study

Tufano, Cláudia Siqueira; Amaral, Ronaldo; Cardoso, Luciana Roberta Donola; Malbergier, André

doi:10.1590/1516-3180.2013.7450010

Cited by 23 publications

(26 citation statements)

References 43 publications

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“…In addition, being a self-assessed measure, the use of the BDI can be related with a response bias. The sociodemographic and economic characteristics of the people living with HIV/Aids evidenced in this study support other background studies developed in Brazil (15,20) and around the world. (10,19,21) In the United States, depression is very common and, according to one study, (11) the overall prevalence rate was estimated at 6.6%, while ranging between 5 and 10% in PLHA.…”

Section: Discussionsupporting

confidence: 89%

“…In Brazil, various studies have been found that assessed depression in PLHA, (13)(14)(15) but none of them assessed the somatic and affective-cognitive symptoms among men and women living with HIV/ AIDS. The pertinence of assessed sex-related particularities is highlighted with a view to understanding the differences and supporting qualified care.…”

Section: Introductionmentioning

confidence: 99%

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Avaliação dos sintomas depressivos somáticos e afetivo-cognitivos de pessoas vivendo com HIV/AIDS

et al. 2017

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Objective: To analyze the somatic and affective-cognitive symptoms of depression according to the sex of people living with HIV/AIDS. Methods: Analytic study developed at specialized care services in Ribeirão Preto-SP, including a sample of 331 participants. To collect the data, a sociodemographic characterization tool and Beck's Depression Inventory (BDI) were used. Results: Among the interviewees, 50.4% were male, 52.1% of whom in the age range between 20 and 35 years. Higher education (p=0.001) and lower income (<0.001) were found for the women and more comorbidities (p=0.004) for the men. It was identified that the women presented higher mean depression scores in the somatic (p<0.001) as well as in the affective/cognitive domains (p<0.001). Conclusion: These study results appoint that the women present higher depressive symptom scores than the man, in the somatic as well as in the affective/cognitive domains of the BDI subscales. ResumoObjetivo: Analisar os sintomas somáticos e afetivo-cognitivos de depressão segundo o sexo de pessoas que vivem com HIV/AIDS. Métodos: Estudo analítico realizado em serviços de atendimento especializado em Ribeirão Preto-SP, com amostra de 331 participantes. Para coleta de dados foram utilizados instrumento de caracterização sociodemográfica e o Inventário de Depressão de Beck (BDI). Resultados: Dos entrevistados, 50,4% eram do sexo masculino e destes, 52,1% estavam na faixa etária de 20 a 35 anos. As mulheres apresentaram maior escolaridade (p=0,001) e menor renda (<0,001), e os homens apresentaram mais comorbidades (p=0,004). Identificou-se que as mulheres apresentaram maiores médias de escores de depressão, tanto no domínio somático (p<0,001) quanto no afetivo/cognitivo (p<0,001). Conclusão: Os resultados deste estudo apontam que as mulheres apresentam maiores escores de sintomatologia depressiva do que os homens, tanto no domínio somático quanto no afetivo/cognitivo das subescalas do IDB.

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Section: Discussionsupporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Avaliação dos sintomas depressivos somáticos e afetivo-cognitivos de pessoas vivendo com HIV/AIDS

et al. 2017

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“…(19) A study demonstrated that support from family and friends to people living with AIDS helped patients to keep their optimism and confidence about the treatment and reduced anxiety and depression. (20) The diagnosis impaired socialization, identified from the need for sociability and evidenced in the practice phenomena becoming sad easily, living alone, fear to expose their ideas and stigma, corroborates the importance of participating in individual and group activities to have an opportunity to enjoy socialization experiences with family and other people with the same disease. (21) Many people who live with AIDS tend to avoid social life to protect themselves.…”

Section: Discussionmentioning

confidence: 91%

“…Family, spouse and other people can participate in the discussion. (19,20) Faced with the impaired adherence to treatment, nurses can implement the following interventions: guide on habits that improve quality of life and encourage people living with AIDS to reveal doubts, anguishes and difficulties related to the treatment, especially immediately after the diagnosis is made, given that patients tend to present irritability, guilt, apathy, among other negative feelings. These reactions can interfere with the commitment to the treatment plan.…”

Section: Discussionmentioning

confidence: 99%

“…Low family support was found in most people in the sample, and it makes patients more prone to suicide. (20,21) The diagnosis fear to die was present in people living with AIDS and is an escape reaction from a negative event that is dreaded. This aspect interferes with the acceptance of the new health condition and can lead to mental health issues, such as anxiety, depression, suicidal ideation and social isolation.…”

Section: Discussionmentioning

confidence: 99%

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Diagnósticos de enfermagem da CIPE® para pessoas com Síndrome da Imunodeficiência Adquirida

et al. 2017

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Objective: To identify ICNP® nursing diagnoses from nursing practice phenomena evidenced in health evaluation of people living with the acquired immunodeficiency syndrome (AIDS). Methods: Cross-sectional study with 120 people living with AIDS at a hospital for the treatment of infectious and contagious diseases. Data collection was carried out using an interview script and a physical exam. Diagnoses were formulated using the ICNP ® guidelines. Data were analyzed through descriptive and inferential statistics. Results: Seventy-two nursing practice phenomena were identified, and 37 diagnoses were given. Among them, 11 reached agreement and content validity indexes > 0.80 and were considered validated. Within this set of diagnoses, seven were categorized in the group of psychobiological needs and four were included in the group of psychosocial demands. Conclusion: The identification of nursing practice phenomena helps to formulate diagnoses, results, and interventions oriented to the essential needs of people living with AIDS. ResumoObjetivo: Identificar diagnósticos de enfermagem da CIPE ® , a partir dos fenômenos da prática de enfermagem evidenciados na avaliação da saúde de pessoas vivendo com a Síndrome da Imunodeficiência adquirida. Métodos: Estudo transversal com 120 pessoas vivendo com Aids em um hospital de doenças infectocontagiosas. Para a coleta de dados empregaram-se um roteiro de entrevista e exame físico. A elaboração dos diagnósticos foi realizada utilizando-se a CIPE ® . Os dados foram analisados por meio da estatística descritiva e inferencial. Resultados: Identificaram-se 72 fenômenos da prática de enfermagem, sendo possível a elaboração de 37 diagnósticos. Destes, apenas 11 obtiveram o índice de Concordância e índice de validação de conteúdo > 0.80, sendo considerados validados; dos quais sete foram classificados dentro das necessidades psicobiologicas e quatro nas psicossociais. Conclusão: A identificação dos fenômenos da prática de enfermagem corrobora na elaboração dos diagnósticos, resultados e intervenções direcionados às necessidades prioritárias de pessoas vivendo com Aids.

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Adherence to antiretroviral therapy for HIV/AIDS in Latin America and the Caribbean: Systematic review and meta‐analysis

et al. 2018

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IntroductionOptimal adherence to antiretroviral therapy is closely related with suppression of the HIV viral load in plasma, slowing disease progression and decreasing HIV transmission rates. Despite its importance, the estimated proportion of people living with HIV in Latin America and the Caribbean with optimal adherence has not yet been reported in a meta‐analysis. Moreover, little is known of the factors leading to poor adherence which may be setting‐specific. We present a pooled estimate of adherence to antiretroviral therapy (ART) of people living with HIV in Latin America and Caribbean, report the methods used to measure adherence and describe the factors associated with poor adherence among the selected studies.MethodsWe electronically searched published studies up to July 2016 on the PubMed, Web of Science and Virtual Health Library (Latin America and the Caribbean Regional Portal); considering the following databases: MEDLINE, LILACS, PAHO and IBECS. Two independent reviewers selected and extracted data on ART adherence and study characteristics. Pooled estimate of adherence was derived using a random‐effects model. Risk of bias in individual studies was assessed independently by two investigators using the Risk of Bias Assessment tool for Non‐randomized Studies (RoBANS).Results and discussionThe meta‐analysis included 53 studies published between 2005 and 2016, which analysed 22,603 people living with HIV in 25 Latin America and Caribbean countries. Overall adherence in Latin America and Caribbean was 70% (95% CI: 63–76; I 2 = 98%), similar to levels identified by studies conducted in high‐income regions. Self‐report was the most frequently used method to measure adherence. Subgroup analysis showed that adherence was higher for the shortest recall time frame used, as well as in countries with lower income level, Gross National Income (GNI) per capita and Human Development Index (HDI). Studies reported diverse adherence barriers, such as alcohol and substance misuse, depression, unemployment and pill burden.ConclusionsOur study suggests that adherence to ART in Latin America and Caribbean may be below the sufficient levels required for a successful long‐term viral load suppression.

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The influence of depressive symptoms and substance use on adherence to antiretroviral therapy. A cross-sectional prevalence study

Cited by 23 publications

References 43 publications

Avaliação dos sintomas depressivos somáticos e afetivo-cognitivos de pessoas vivendo com HIV/AIDS

Avaliação dos sintomas depressivos somáticos e afetivo-cognitivos de pessoas vivendo com HIV/AIDS

Diagnósticos de enfermagem da CIPE® para pessoas com Síndrome da Imunodeficiência Adquirida

Adherence to antiretroviral therapy for HIV/AIDS in Latin America and the Caribbean: Systematic review and meta‐analysis

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