Effects of continuous vs interval exercise training on oxygen uptake efficiency slope in patients with coronary artery disease

Abstract

The oxygen uptake efficiency slope (OUES) is a submaximal index incorporating cardiovascular, peripheral, and pulmonary factors that determine the ventilatory response to exercise. The purpose of this study was to evaluate the effects of continuous exercise training and interval exercise training on the OUES in patients with coronary artery disease. Thirty-five patients (59.3±1.8 years old; 28 men, 7 women) with coronary artery disease were randomly divided into two groups: continuous exercise training (n=18) and interval exercise training (n=17). All patients performed graded exercise tests with respiratory gas analysis before and 3 months after the exercise-training program to determine ventilatory anaerobic threshold (VAT), respiratory compensation point, and peak oxygen consumption (peak VO2). The OUES was assessed based on data from the second minute of exercise until exhaustion by calculating the slope of the linear relation between oxygen uptake and the logarithm of total ventilation. After the interventions, both groups showed increased aerobic fitness (P<0.05). In addition, both the continuous exercise and interval exercise training groups demonstrated an increase in OUES (P<0.05). Significant associations were observed in both groups: 1) continuous exercise training (OUES and peak VO2 r=0.57; OUES and VO2 VAT r=0.57); 2) interval exercise training (OUES and peak VO2 r=0.80; OUES and VO2 VAT r=0.67). Continuous and interval exercise training resulted in a similar increase in OUES among patients with coronary artery disease. These findings suggest that improvements in OUES among CAD patients after aerobic exercise training may be dependent on peripheral and central mechanisms.

Effects of High-Intensity Interval Training on Aerobic Capacity in Cardiac Patients: A Systematic Review with Meta-Analysis

“…The authors of seventeen studies [10, 12, 13, 20–23, 25–29, 31, 33, 35–37] involving 611 patients reported on peak heart rate following INTERVAL and CONTINUOUS. A random-effects model revealed no significant difference between groups (MD 0.97 bpm, 95% CI −2.19 to 4.12 bpm, p = 0.55).…”

Effects of Interval Aerobic Training Program with Recovery bouts on cardiorespiratory and endurance fitness in seniors

“…30,31 Globally, in spite of a reduced total volume of physical activity, IATP-R induced also enhancement in aerobic capacities of similar extends to which previously reported with common IATP. Thus, in seniors, Coker et al, 32 Foster et al, 33 Perini et al, 24 and Vogel et al 10 reported a significant improvement in VO 2peak of 14%-17% after 9-12 week of IATP. This magnitude of VO 2peak enhancement was also similar to those measured after medium-(ie, 14-24 weeks) 34,35 and long-term (ie, >24 weeks) 36 37 Furthermore, VO 2peak is also considered as the most powerful predictor of mortality compared to other wellestablished risk factors.…”

“…21 The great adherence rate reported with IATP-R was much higher than those usually reported with common IATP. [22][23][24][25] It was explained by the design of the program that was supervised and personalized. These criteria are known to be more effective in reducing the risk of injury and in improving performance among seniors compared to home-based or un-supervised programs.…”

Cardiopulmonary Exercise Testing for Preoperative Evaluation: What Does the Future Hold?

“…Although encouraging, the data supporting the prognostic value of OUES is limited to date due to a lack of appropriately powered prospective studies and warrants further investigation. The OUES displays prognostic value in patients with HF [49][50][51] and coronary artery disease (CAD) [52,53] and has been shown to be responsive to physical training in patients with CAD [54,55].…”