2013
DOI: 10.1590/1414-431x20132666
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Abstract: The maintenance of extracellular Na+ and Cl- concentrations in mammals depends, at least in part, on renal function. It has been shown that neural and endocrine mechanisms regulate extracellular fluid volume and transport of electrolytes along nephrons. Studies of sex hormones and renal nerves suggested that sex hormones modulate renal function, although this relationship is not well understood in the kidney. To better understand the role of these hormones on the effects that renal nerves have on Na+ and Cl- r… Show more

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Cited by 9 publications
(2 citation statements)
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“…E 2 relaxes rat renal arteries contracted with acetylcholine [ 42 ]. E 2 and P 4 also regulate renal catecholamine release, which can change renal blood flow [ 43 ]. In contrast to UBF, acute E 2 and/or P 4 treatment did not influence renal artery blood flow, and there was no difference in the renal artery response to hormones between WT and CSE KO mice ( Fig.…”
Section: Resultsmentioning
confidence: 99%
“…E 2 relaxes rat renal arteries contracted with acetylcholine [ 42 ]. E 2 and P 4 also regulate renal catecholamine release, which can change renal blood flow [ 43 ]. In contrast to UBF, acute E 2 and/or P 4 treatment did not influence renal artery blood flow, and there was no difference in the renal artery response to hormones between WT and CSE KO mice ( Fig.…”
Section: Resultsmentioning
confidence: 99%
“…The GFR was determined by creatinine clearance (calculated as (U c × V)/P cr , where U cr is urinary concentration of creatinine (mg ml − 1 ), V is urinary flow (ml min − 1 ) and P cr is plasma concentration of creatinine (mg ml − 1 ). 18 At the end of each experiment, the animals were decapitated, and a blood sample was taken to measure plasma creatinine. The kidneys and left ventricle were removed and decapsulated, and the left ventricle and kidney weight/body weight ratios were determined.…”
Section: Surgical Procedures and Experimental Designmentioning
confidence: 99%