Prescrições medicamentosas de pacientes atendidos no ambulatório de geriatria de um hospital universitário: estudo transversal descritivo

Cuentro, Vanessa da Silva; Andrade, Milene Aparecida; Gerlack, Letícia Farias; Bós, Ângelo José Gonçalves; Silva, Marcos Valério Santos da; Oliveira, Alex Ferreira de

doi:10.1590/1413-81232014198.09962013

Cited by 19 publications

(25 citation statements)

References 30 publications

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“…Brazilian studies have identified a prevalence of polypharmacy of between 11.0% and 71.1%, with the highest frequency among elderly persons with MS [27][28][29][30] . The higher prevalence of chronic illnesses among elderly persons leads to an ongoing increase in the consumption of medications in this age range.…”

Section: Discussionmentioning

confidence: 99%

“…There is evidence that the prescription of PIM is associated with the triggering of DI and hospitalizations and, when combined with the presence of comorbidities and polypharmacy, exposes the elderly to a high risk of mortality 7 . The lack of cost-effective therapeutic alternatives with a safer profile for these individuals in public health adds to this risk 27 . to the severity and prevalence of possible DI 33 .…”

Section: Discussionmentioning

confidence: 99%

“…The association between the presence of possible DI and age found in the present study diverged from an investigation of elderly persons living in the community in the city of Rio de Janeiro 11 . The relationship between increasing age and the occurrence of DI deserves further investigation 10,11 , as the aging process may contribute to the increase in the prevalence of chronic diseases, which causes the elderly to use more drugs 7 , resulting in a greater possibility of DI 10,27 .…”

Section: Discussionmentioning

confidence: 99%

“…The use of PIM and the presence of DI are factors that are directly related to the quality of life of the elderly, either acting alone or in association with physiological changes and comorbidities, which reinforces the need for evaluation of the therapeutic plan, since the greater the number of drugs prescribed, the greater the risk of the use of PIM and exposure to DI 35 . It is essential to assess the risks and benefits related to prescribed pharmacotherapy, with doses monitored and/or reduced, as many interactions may reduce the effectiveness of medications 27 . Thus, health professionals should be aware of information about DI and propose appropriate interventions when necessary.…”

Section: Discussionmentioning

confidence: 99%

“…These conditions require constant monitoring, since their effects can worsen the clinical condition of the elderly, which may result in the need for additional treatment, hospitalization, costs to the health system, or if the elderly person is already hospitalized, lead to a longer hospitalization period. One way to address this is by selecting drugs that do not produce interactions, however, if there is no such possibility, the drugs that interact with each other should be monitored 27 .…”

Section: Discussionmentioning

confidence: 99%

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Profile of elderly persons with metabolic syndrome and factors associated with possible drug interactions

Tavares

Gomes

Rodriguês

et al. 2018

Rev. bras. geriatr. gerontol.

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Objectives: To describe the sociodemographic, clinical and pharmacotherapy characteristics of elderly persons with metabolic syndrome and to identify factors associated with drug interactions among these individuals. Method: A quantitative, analytical and transversal study was carried out among 263 elderly people with metabolic syndrome in the urban area of Uberaba, Minas Gerais, Brazil. Possible drug interactions were identified and classified according to the Micromedex® DrugReax System. The chi-squared test and the multiple logistic regression model were used for analysis ( p<0.05). Results: The majority of the individuals were female (70.7%); aged 60 to 74 years (72.3%); lived with a spouse/ partner (63.9%); had some schooling (74.1%); an individual monthly income of ≤ one minimum wage (77.1%); lived with others (88.2%); had five or more morbidities (89.7%) and exhibited polypharmacy (73.0%); used potentially inappropriate medications (54.4%) and had possible drug interactions (75.3%). Associated with the possible presence of drug interactions were: age range ( p=0.005), polypharmacy ( p<0.001) and use of potentially inappropriate medications ( p=0.006). Conclusion: Possible drug interactions were associated with increased age, polypharmacy and the use of potentially inappropriate medications. This study contributes to knowledge of these possible interactions among elderly people with metabolic syndrome, and as such can be considered an important tool for planning actions to ensure the safety of these individuals who, due to the complexity of their treatment, use multiple medications.

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Section: Discussionmentioning

confidence: 99%