Treatment of Infection After Total Knee Arthroplasty

Abstract

Objectives: To identify and compare the rate of success of therapeutic modalities applied in surgeries for the treatment of infections associated with total knee arthroplasty (TKA), and to evaluate the functional outcome and pain in different therapeutic modalities by means of quality of life scores. Methods: We evaluated all patients who developed periprosthetic infection after TKA for primary or secondary osteoarthritis, in the period from January 1st, 2008 to December 31st, 2010. Results: In the study period, 29 patients with TKA had infection, and 12 of these underwent debridement and retention of the prosthesis (D+R), seven received two-stage and six one-stage exchange arthroplasties, and four patients were treated with suppressive antibiotic therapy because they could not undergo another surgical procedure. Conclusion: The D+R, one-stage revision and two-stage revision success rates were 75%, 83.3%, and 100%, respectively. The best results of quality of life (QoL) and function occur in patients undergoing D+R. In contrast, the worst QoL and functional results were obtained in patients treated with two-stage revision arthroplasty. Level of Evidence II, Prognostic Studies - Investigating the Effect of a Patient Characteristic on the Outcome of Disease.

Common Post Lower Limb Arthroplasty Complications, Management Approaches and How to Minimize the Risks

“…8 Most common agent of peri-prosthetic infection is Staphylococcus aureus, followed by coagulasenegative Staphylococcus and Streptococcus for total knee replacement. 1,3,9 Delayed infections may present with subtler symptoms which are for example joint pain and early loosening. These are caused by low-virulent organisms (coagulase-negative staphylococci or Cutibacterium species).…”

Two-Stage Treatment of Periprostetic Infection: Mid-Term Results

“…По данным систематического обзора литературы, средний показатель успешности лечения ППИ после двухэтапной ревизии составляет 89,8% [22], хотя ряд авторов приводят результат 93-100% [23,24]. частота реинфекции в группе пациентов после реимплантации составляет 14,6-28,0% [13,25,26,27].…”

Infection after total knee arthroplasty and its gold standard surgical treatment: Spacers used in two-stage revision arthroplasty

“…Postsurgical prosthesisrelated infections are rare but nonetheless one of the most devastating postoperative complications (6). Numerous factors contribute to the rate of infection; despite the development of infection control, rates of infection are still as high as 3% (6)(7)(8).…”