IMUNOLOCALIZAÇÃO DE ENTEROGLUCAGON EM CÉLULAS ENDÓCRINAS PRESENTES NO ESTÔMAGO DO MUÇUÃ &lt;italic&gt;Kinosternon scorpioides&lt;/italic&gt; (REPTILIA, CHELONIA, KINOSTERNIDAE)

Pereira, José Gomes; Silva, Silvana Regina; Gonçalves, M. T. C.; Melo, Ferdinan Almeida; Viana, Diego Carvalho; Oliveira, Antônia Santos; Machado, C. R.

doi:10.1590/1089-6891v16i330969

Cited by 1 publication

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References 11 publications

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“…Many hormones, such as the regulator peptides, appear to act in the integration of the innumerable functions performed by the body; besides, they perform important regulatory actions in the physiological function of digestive tract cells (Fujita 1990;Larsson 2000;Huang & Wu 2005;Pereira et al 2015). Moreover, secretory cells play an important role in lubricating the organ and protecting it from pro-teolytic degeneration and pathogenic microorganisms (Reid et al 1988).…”

Section: Introductionmentioning

confidence: 99%

Immunohistochemical study of the six types of endocrine cells in the enteropancreatic system of the lizard Tropidurus torquatus (Squamata: Tropiduridae)

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Cardoso

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et al. 2017

The European Zoological Journal

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The present study investigates the aspects of endocrine cells secreting cholecystokinin, gastrin, insulin, glucagon, somatostatin and serotonin in the enteropancreatic system of Tropidurus torquatus. The specimens were collected in Marambaia Island, Sepetiba Bay, Rio de Janeiro State, Brazil. The animals' intestine and pancreas were removed, fixed, processed and then subjected to immunohistochemical techniques. Three cell types, immunoreactive (IR) to gastrin, cholecystokinin-8 and serotonin, were identified in the intestinal mucosa. Serotonin was found in the small and large intestines, whereas gastrin and cholecystokinin-8 cells were only observed in the large intestine of T. torquatus. Glucagon, somatostatin and insulin were not observed in the intestines at all. Only glucagon, somatostatin and insulin were identified in the pancreas of the studied lizards. The dorsal lobe showed a large number of endocrine cells scattered throughout the exocrine parenchyma and in the exocrine duct walls. The present study shows that the intestine and pancreas of T. torquatus hold most of the regulatory peptides, presenting a structure similar to that in other vertebrates such as birds and mammals. The endocrine cells identified in the lizards' enteropancreatic system evidences the good phylogenetic preservation of the regulatory peptides' molecular structure.

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