2020
DOI: 10.1590/0104-1428.03820
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Abstract: The emergence of antibiotic resistance in microorganisms is a serious challenge globally. Natural hydrophobic diterpene carboxylic acids present in rosin have unsatisfactory inhibitory properties against pathogens due to their poor water solubility. Therefore, the objective of research work was to modify the natural rosin into rosin maleic anhydride adduct with improved bioinhibitory properties for methicillin-resistant Staphylococcus aureus (MRSA). Prescreened MRSA isolates were found 78.05% and 29.27% resist… Show more

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Cited by 4 publications
(2 citation statements)
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References 17 publications
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“…This behavior is related to the interruption of proton transfer in the membrane-related adenosine triphosphatase (ATPase) and leads to the uncoupling of oxidative phosphorylation. It leads to the metabolism of cells can stop and the source of energy is vanished 31 .…”
Section: Introductionmentioning
confidence: 99%
“…This behavior is related to the interruption of proton transfer in the membrane-related adenosine triphosphatase (ATPase) and leads to the uncoupling of oxidative phosphorylation. It leads to the metabolism of cells can stop and the source of energy is vanished 31 .…”
Section: Introductionmentioning
confidence: 99%
“…Dehydroabietic, abietic, levopimaric, neoabietic, palustric, and isopimaric acids make up the majority of the hydrophobic diterpene carboxylic acids that make up rosin [ 15 ]. The confirmation of antibacterial effectiveness against numerous types of microbes was supplied by in vitro tests [ 16 , 17 , 18 , 19 ]. Skin sores and lesions have been seen to heal after rosin therapy [ 20 , 21 ].…”
Section: Introductionmentioning
confidence: 99%