Chronic liver disease in cattle associated with ingestion of  Brachiaria spp.

Faccin, Tatiane Cargnin; Kommers, Gláucia D.; Galiza, Glauco José Nogueira de; Pupin, Rayane C.; Madureira, Renata Cunha; Lemos, Ricardo A.A.

doi:10.1590/0103-8478cr20160297

Cited by 4 publications

(4 citation statements)

References 8 publications

(21 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The density of Fasciola spp is highly associated to the severity of hepatic fibrosis and hyperplasia of bile ducts in naturally infected cattle (Marcos et al, 2007). Bile duct hyperplasia, periportal fibrosis as well as lymphocytic infiltration were also found in cattle livers by Faccin et al, 2016 which is in agreement with present findings. Granulomatous inflammation was characterized by the focal infiltration of mononuclear cells in the cattle and goat liver with a nodular appearance.…”

Section: Discussionsupporting

confidence: 92%

Anatomic pathology of cattle and goat liver collected from slaughterhouses in Mymensingh city of Bangladesh

Akter¹,

DC²,

Sultana³

et al. 2022

JAFE

View full text Add to dashboard Cite

The morphologic abnormality of cattle and goat livers (collected from slaughterhouses in Mymensinghcity of Bangladesh) were investigated in the present study. The livers of slaughtered cattle (n = 14) and goat (n = 20) were examined by gross visualization, palpation and incision as well as histopathology. The total liver lesion in cattle was 71.4% and in goat was 75%. Grossly, various pathological changes, mainly thickened, rough capsule which was whitish in color, necrotic foci, thickened bile ducts with matured flukes, fibrosis were seen. Histopathologically, necrosis, degenerative changes of hepatocytes, dilated sinusoids, inflammatory infiltrates, granuloma, bile duct hyperplasia, periportal and periductal fibrosis were found in cattle and goat livers. Extensive fibrosis was seen portal areas of liver by Goldner’s trichrome staining. Migratory tracts and immature flukes were seen in intrahepatic bile ducts. Most common cause of liver lesions found in the present study was Fascioliasis in both cattle and goat. It could be concluded that the major gross and microscopic alterationsin the livers of cattle and goat due to Fasciola giganticainfectionreflected tissue damage, which can lead to substantial financial losses in animals and great health problems in human. Therefore, special care and attention are required to ensure that seriously damaged livers of food animals are not passed on for human consumption, and extensive monitoring and epidemiological surveys are necessary to cope this adverse situation

show abstract

Section: Discussionsupporting

confidence: 92%

Anatomic pathology of cattle and goat liver collected from slaughterhouses in Mymensingh city of Bangladesh

Akter¹,

DC²,

Sultana³

et al. 2022

JAFE

View full text Add to dashboard Cite

show abstract

“…En cuanto a los hígados con fibrosis, constituyen un 8% del total y se debe a una respuesta reparativa descompensada junto con lesión epitelial persistente, muerte y regeneración errónea de miofibroblastos activados (Horowitz y Thannickal, 2019). Según Faccin et al (2016), una evolución de la fibrosis es la atrofia hepá- tica (2%) apreciando un aumento de un lóbulo hepático y disminución del contiguo (atrofia). La evolución a atrofia hepática también puede ser debido a desnutrición, déficit de factores hepatotrópicos o por pérdida de chalonas, pero su principal causa es la fibrosis (Roger, 2002).…”

Section: Discussionunclassified

Estudio Anatomopatológico Y Mastocitos en Hígados De Ternero Decomisados en Matadero

MURCIA¹,

Martínez²,

Sánchez³

et al. 2022

An. Vet. Murcia

View full text Add to dashboard Cite

This study research the anatomopathological injuries and the number of mast cells in 51 confiscated calf livers in a major slaughterhouse in the south-east of Spain. The microscopic analysis was realized with hematoxylin-eosin (H-E) and Masson's Trichrome (CRT) stains. Furthermore, the number of mast cells was determined based on their pathologies, using toluidine blue staining, counting in 10 fields of 348 x 263 µm at 40x in each of the samples and with the SPSS statistical program and the Kolmogorov-Smirnov and Mann-Whitney tests compared with 5 control livers. The pathological lesions of confiscation were: abscesses (47%), cholangiohepatitis (31%), fibrosis (8%), steatosis (6%), atrophy (2%), necrosis (2%), congestion (2%) and cyst (2%). Classifying into inflammatory lesions (49%), parasitic lesions (33%) and degenerative-metabolic lesions (18%). The results conclude that there are significant differences in the number of mast cells in livers with cholangiohepatitis (p 0,001) compared with control livers and there are no significant differences in livers with abscesses (p 0,227). When classifying the pathological alterations by families, there are no significant differences in the inflammatory alterations when compared them with the control group and there are differences in the parasitic alterations. Degenerative alterations show significative differences, but the number of samples collected is scarce. Este estudio aborda las alteraciones anatomopatológicas y el número de mastocitos en 51 hígados de ternero decomisados en un matadero importante del sur-este de España. El análisis microscópico se ha realizado con las tinciones hematoxilina-eosina (H-E) y Tricrómico de Masson (TRC). Además, se determinó el número de mastocitos en función de sus patologías, mediante la tinción azul de toluidina, haciendo un conteo en 10 campos de 348 x 263 µm a 40x en cada una de las muestras. Con el programa estadístico SPSS y las pruebas estadísticas Kolmogorov-Smirnov y Mann-Whitney se ha hecho una comparación con 5 hígados control. Las lesiones anatomopatológicas causantes de decomiso han sido: abscesos (47%), colangiohepatitis (31%), fibrosis (8%), esteatosis (6%), atrofia (2%), necrosis (2%), congestión (2%) y quiste (2%). Clasificándose en lesiones inflamatorias (49%), lesiones parasitarias (33%) y lesiones degenerativo-metabólicas (18%). Los resultados del conteo de mastocitos muestran que hay diferencias significativas en el número de mastocitos de los hígados con colangiohepatitis (p 0,001), respecto a los hígados control y no hay diferencias significativas en los hígados con abscesos (p 0,227). Al hacer una clasificación por familias de las alteraciones anatomopatológicas estudiadas se ha llegado a la conclusión de que no hay diferencias significativas en las alteraciones inflamatorias al compararlas con el grupo control y sí las hay en las alteraciones parasitarias. Las alteraciones degenerativas también muestran diferencias significativas, pero el número de muestras recogidas es bajo.

show abstract

“…It is notable that the cause of hepatic bile duct hyperplasia is usually fascioliasis. The most commonly observable bovine hepatic diseases in abattoirs are telangiectasia, hepatitis, perihepatitis (adhesions), fascioliasis, hydatidosis, tuberculosis, abscess, and Cirrhosis (fibrosis) (22). In a research on buffalo livers affected by Fasciola gigantica performed in Hyderabad's Abattoir in Pakistan, the results of microscopic observations of the affected livers revealed severe damages and subsequent breakdown of hepatic cords, inflammation, atrophy, and necrosis.…”

Section: Discussionmentioning

confidence: 99%

Pathology and prevalence of hepatic lesions of Azeri buffaloes (bubalus bubalis) slaughtered at Urmia Abattoir, Northwest Iran

Alizadeh

Amniattalab

2020

JFSH

View full text Add to dashboard Cite

This study was carried out for the evaluation of the prevalence rate and the pathology of various lesions in the confiscated livers of slaughtered Azeri buffaloes at Urmia Abattoir, Northwest Iran. Livers of 306 Azeri buffaloes were inspected grossly during five months according to their color and consistency changes in Urmia Abattoir. Among the inspected carcasses, livers of 28 buffaloes had various lesions. The collected tissue samples of confiscated livers were placed in 10% buffered formalin as a fixative solution in order to prepare pathologic sections with a thickness of 6 μm. The sections were stained by haematoxylin and eosin (H&E) and periodic acid schiff (PAS) methods. The most common pathologic changes in the confiscated buffalo livers were fatty change (46.4%), hepatitis and cholangitis (42.9%), and bile duct hyperplasia (39.3%) respectively. The results of this study have shown that there was a significant difference (p<0.05) between hepatic congestion and sex. In addition, there was no significant difference (p>0.05) between hepatic lesions and age. The results of this study have revealed that fascioliasis has an important role in the creation of some hepatic lesions such as bile duct hyperplasia, fatty change, and hepatitis in buffaloes. Since various hepatic lesions can reduce buffalo productions and has negative influence on animal reproduction, it is necessary to pay more attention to accurate performing of antiparasitic program and the evaluation of possible role of poisonous plants, heavy metals, and mycotoxins in the generation of hepatic lesions of buffaloes.

show abstract

Chronic liver disease in cattle associated with ingestion of Brachiaria spp.

Cited by 4 publications

References 8 publications

Anatomic pathology of cattle and goat liver collected from slaughterhouses in Mymensingh city of Bangladesh

Anatomic pathology of cattle and goat liver collected from slaughterhouses in Mymensingh city of Bangladesh

Estudio Anatomopatológico Y Mastocitos en Hígados De Ternero Decomisados en Matadero

Pathology and prevalence of hepatic lesions of Azeri buffaloes (bubalus bubalis) slaughtered at Urmia Abattoir, Northwest Iran

Contact Info

Product

Resources

About