Chemical composition of essential oil extracted from leaves of Campomanesia adamantium subjected to different hydrodistillation times

Oliveira, Juliana Dantas de; Alves, Daniely Karen Matias; Miranda, Mayker Lázaro Dantas; Alves, José Milton; Xavier, Marcelo Nogueira; Cazal, Cristiane de Melo; Alves, Cássia Cristina Fernandes

doi:10.1590/0103-8478cr20151131

Cited by 13 publications

(4 citation statements)

References 14 publications

(8 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study, continuing our line of research on chemical composition and the biological activities of essential oils (Lemes et al, 2017;Oliveira et al, 2017), analyzes the chemical composition and the antibacterial and antiproliferative activities of the fresh leaf essential oil of P. guajava L. collected in the southwest region of the state of Goiás.…”

Section: Introductionmentioning

confidence: 86%

Antibacterial and antiproliferative activities of the fresh leaf essential oil of Psidium guajava L. (Myrtaceae)

et al. 2019

View full text Add to dashboard Cite

This study evaluated the antibacterial and antiproliferative activities of the essential oil of Psidium guajava leaves (PG-EO), traditionally used in folk medicine. The essential oil was obtained from fresh leaves by hydrodistillation, using a modified Clevenger apparatus. The major PG-EO chemical constituents were identified by GC-MS and GC-FID as being β-caryophyllene (16.1%), α-humulene (11.9%), aromadendrene oxide (14.7%), δ-selinene (13.6%), and selin-11-en-4α-ol (12.5%). The antibacterial activity of the essential oil of P. guajava leaves was determined in terms of its minimum inhibitory concentrations (MIC) using the broth microdilution method in 96-well microplates. PG-EO had moderate activity against Streptococcus mutans (MIC = 200 µg/mL), S. mitis (MIC = 200 µg/mL), S. sanguinis (MIC = 400 µg/mL), S. sobrinus (MIC = 100 µg/mL), and S. salivarius (MIC = 200 µg/mL). The antiproliferative activity was evaluated against different tumor cell lines: breast adenocarcinoma (MCF-7), human cervical adenocarcinoma (HeLa), and human gliobastoma (M059J). A normal human cell line (GM07492A, lung fibroblasts) was included. The antiproliferative activity was evaluated using the XTT assay and the results were expressed as IC50. The essential oil showed significantly lower IC50 values against MCF-7 and M059J lines than that obtained for the normal line, showing selectivity. Our results suggest that the essential oil of Psidium guajava L. has promising biological activities and can be considered a new source of bioactive compounds.

show abstract

Section: Introductionmentioning

confidence: 86%

Antibacterial and antiproliferative activities of the fresh leaf essential oil of Psidium guajava L. (Myrtaceae)

et al. 2019

View full text Add to dashboard Cite

show abstract

“…The seeds and fruits were shade dried for 72 h and pulverised using a manual blender (Corona, Landers Colombia). The ground seeds of M. myristica (0.90 kg) and fruits X. aethiopica (0.65 kg) were maintained with distilled water (5 L) at 35 ± 2 °C for 7 days to properly macerate them and separately subjected to hydrodistillation using an all-glass Clevenger apparatus (Deschem Equipment Co. Ltd) for 4 h according to the method described by Oliveira et al (2017) with slight modifications. To ensure high quality of the essential oil extracted, extraction was done from one batch each of the X. aethiopica fruit and M. myristica seed harvested from the same plant in the same month.…”

Section: Methodsmentioning

confidence: 99%

Behavioural and biochemical indications of the antidepressant activities of essential oils from Monodora myristica (Gaertn) seed and Xylopia aethiopica (Dunal) fruit in rats

Ekeanyanwu

Nkwocha

Ekeanyanwu

2021

IBRO Neuroscience Reports

View full text Add to dashboard Cite

Monodora myristica and Xylopia aethiopica are two underutilised spices that are hypothesized to be important in the management and treatment of certain stress-induced diseases such as depression. The present study was designed to test the anti-depressant effects of the essential oils of Monodora myristica (EOMM) and Xylopia aethiopica (EOXA) and the possible underlying mechanisms in a chronic unpredictable mild stress (CUMS) - induced depression in the rat. Forty-two male Wistar rats were assigned to seven groups (n = 6); group I received corn oil (p.o, unstressed control), group II (stressed control) administered corn oil, groups III-IV received EOMM (150 & 300 mg/kg, p.o), groups V – VI received EOXA (150 & 300 mg/kg, p.o) whereas group VII had fluoxetine (10 mg/kg, p.o in d/w). Corn oil served as the vehicle for the delivery of the essential oils and the doses were administered via gastric intubation to rat once daily for six consecutive weeks from the 2nd week. Open-field, tail suspension (TST), and forced swimming (FST) tests were used to evaluate the behavioural activity in addition to the biochemical parameters (catalase, superoxide dismutase, reduced glutathione, monoamine oxidase, corticosterone, protein carbonyl compound, malondialdehyde and nitric oxide). The result showed that the administration of EOMM (150 and 300 mg/kg b.wt.) and EOXA (150 and 300 mg/kg b.wt.) during CUMS significantly ameliorated these behavioural activities and some biochemical parameters in rats. EOMM and EOXA exhibited significant antidepressant-like effects in a rat model of CUMS. At treatment doses of especially 300 mg/kg b.wt, the antidepressant effects of EOMM and EOXA are comparable to a standard antidepressant drug, fluoxetine (Prozac ™). The EOXA especially at a dose of 300 mg/kg b.wt is more effective than EOMM even at 300 mg/kg dose level in ameliorating depression in stressed rats. In conclusion, the study revealed that both the EOXA and EOMM relieved depression-like states through the mitigation of oxidative stress with a reduction in serum Corticosterone (CORT) and brain Monoamine Oxidase-A (MAO-A) levels.

show abstract

“…The duration of time the plant parts are exposed to the procedure can vary among studies, but nonetheless, evidence suggests that yield is fairly constant at economically viable values (Table 1). For example, with leaves from C. adamantium, yield after two hours of extraction (0.3% w/w) was similar to that after 2 -5 hours, but at longer time intervals, more compounds were extracted (Oliveira et al, 2017). In contrast, with dried leaves of C. adamantium, the yield after four hours 0.5% v/w (Oliveira et al, 2016) was half that after two hours in another study (1%, Sá et al, 2018).…”

Section: Chemistry Of Campomanesia Essential Oilsmentioning

confidence: 73%

A review of essential oils and their properties in the genus Campomanesia (Myrtaceae) from the Brazilian Cerrado

Bin

Silva

Valladão

et al. 2022

RSD

View full text Add to dashboard Cite

O gênero Campomanesia (Myrtaceae) compreende espécies de interesse econômico e científico. Produzem óleos essenciais (OE), extraídos a partir das folhas, frutos, sementes, raízes e casca. Das espécies de Campomanesia, 14 são encontradas no bioma Cerrado, um dos maiores domínios fitogeográficos brasileiros e é hotspot de biodiversidade e espécies endêmicas. O objetivo foi compreender os OE do gênero Campomanesia do Cerrado brasileiro, revisar as espécies e os constituintes bioativos desses óleos. Foram utilizadas as bases de dados Scopus, Web of Science, PubMed, Directory of Open Access Journal, Science Direct, com as palavras-chave: “essential oil” and “Campomanesia” combinada com o nome das espécies do Cerrado. Nas 37 publicações resultantes, há uma variedade de OE potenciais descritos, a maioria dos quais com atividades antimicrobiana e antioxidante. C. adamantium e C. pubescens foram as mais citadas e cinco espécies no gênero não foram incluídas pelos critérios de pesquisa. Compostos com potencial atividade biológica incluem os monoterpenos como os principais constituintes dos óleos voláteis dos frutos, enquanto os sesquiterpenos são compostos majoritários nas partes restantes das plantas. Assim, os OE da Campomanesia fornecem alternativas potencialmente interessantes e viáveis para alimentação e terapêutica. O uso sustentável da biodiversidade, aliado à biotecnologia, é o caminho para desenvolver produtos mais naturais ou compostos que se combinem sinergicamente com produtos sintéticos, reduzindo as concentrações necessárias para atingir o efeito desejado. Assim, com as muitas espécies de Campomanesia no Cerrado, a conservação da biodiversidade pode ser aliada ao uso sustentável e proporcionar benefícios, da mesa à farmácia, em futuro próximo.

show abstract

Chemical composition of essential oil extracted from leaves of Campomanesia adamantium subjected to different hydrodistillation times

Abstract: Campomanesia adamantium is a native fruit species of the Cerrado and is used in food and

Cited by 13 publications

References 14 publications

Antibacterial and antiproliferative activities of the fresh leaf essential oil of Psidium guajava L. (Myrtaceae)

Antibacterial and antiproliferative activities of the fresh leaf essential oil of Psidium guajava L. (Myrtaceae)

Behavioural and biochemical indications of the antidepressant activities of essential oils from Monodora myristica (Gaertn) seed and Xylopia aethiopica (Dunal) fruit in rats

A review of essential oils and their properties in the genus Campomanesia (Myrtaceae) from the Brazilian Cerrado

Contact Info

Product

Resources

About