Vitamin D Levels and Lipid Profile in Patients Undergoing Bariatric Surgery

Abstract

BACKGROUND: Vitamin, mineral, and metabolic deficiencies occur in the postoperative period of bariatric surgery, in the short and long term, and are worrisome intercurrences. AIMS: To evaluate the association of serum vitamin D levels with the lipid profile in obese patients undergoing bariatric surgery. METHODS: Case series of patients assisted from 2010 to 2018, in a private hospital of medium and high complexity, who underwent bariatric surgery using sleeve gastrectomy or Roux-en-Y gastric bypass techniques, monitored by the same surgeon. Sociodemographic, clinical, laboratory, and anthropometric data were collected preoperatively and at 6, 12, and 24 months after surgery. RESULTS: A total of 156 individuals, mostly female (75.6%) were monitored. The most frequent comorbidities were hepatic steatosis (76.3%) and hypertension (48.27). Regarding preoperative vitamin D levels, only 18.9% of the population had a satisfactory level (≥30 ng/mL). There was a reduction in weight and an improvement in the lipid profile after surgery. Significant correlations were observed between the lipid profile and vitamin D concentration only in the sample submitted to the Roux-en-Y gastric bypass technique: negative correlation between total cholesterol and vitamin D two years after surgery; positive correlation between triglycerides and vitamin D one year after surgery; and negative correlation between high-density lipoprotein and vitamin D two years post-surgery. CONCLUSIONS: It is essential to routinely monitor vitamin D levels and lipid profile pre- and postoperatively in order to avoid damage associated with this vitamin deficiency.

Laparoscopic Sleeve Gastrectomy Versus Laparoscopic Roux-en-Y Gastric Bypass for Weight Loss in Obese Patients: Which Is More Effective? A Systematic Review and Meta-Analysis

“…Excessive body fat increases the risk of complications in obese people, reducing their quality of life. The risk of having diabetes mellitus type 2 (DM2) increases proportionally to the rise in body mass index (BMI), being more pronounced in those above 30 kg/m 20 , 37 . There is also a directly proportional relationship between BMI value and high blood pressure values, so the prevalence rate of arterial hypertension (AH) in obese people is double that in thin patients 28 .…”

“…The risk of having diabetes mellitus type 2 (DM2) increases proportionally to the rise in body mass index (BMI), being more pronounced in those above 30 kg/m 2 of BMI 18 . In addition, obesity is related to lipid disorders, such as hypertriglyceridemia, low high-density lipoprotein (HDL) concentration, and increased low density lipoprotein (LDL) concentration 20,37 . There is also a directly proportional relationship between BMI value and high blood pressure values, so the prevalence rate of arterial hypertension (AH) in obese people is double that in thin patients 28 .…”