The Effect of Ileocecal Valve Removal in a Model of Short Bowel Syndrome

Soler, Wangles; Lee, Andre Dong; D’Albuquerque, Eugênia Machado Carneiro; Capelozzi, Vera Luíza; Albuquerque, Luiz C. de; Capelhuchnick, Peretz; Lancelotti, Carmem Penteado; Galvão, Flávio Henrique Ferreira

doi:10.1590/0102-672020180001e1417

Cited by 6 publications

(6 citation statements)

References 15 publications

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“…Antibiotic prophylaxis should be administered to patients undergoing clean procedures involving prosthesis or implant placement (for example, inguinal hernia with mesh), clean-contaminated and contaminated operations 29 . It should not be used routinely in clean operations, unless they involve the placement of prostheses or implants.…”

Section: Resultsmentioning

confidence: 99%

What’s New in Infection on Surgical Site and Antibioticoprophylaxis in Surgery?

Costa

Santa‐Cruz

Ferraz

2020

ABCD, arq. bras. cir. dig.

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Introduction: Infection of the surgical site is the common complication, with significant rates of morbidity and mortality, representing a considerable economic problem for the health system. Objective: To carry out a narrative review of the literature on surgical site infection and the principles of antibiotic prophylaxis to update the knowledge of its use in surgery. Method: Medline, Ovid, Google Scholar, National Library of Medicine (PubMed), Cochrane and SciELO were used for the research. The keywords used were “anti-bacterial agents”; “antibioticoprophylaxis” AND “surgical wound infection”. The inclusion criteria were articles of recent publication, with full texts available and performed in humans. Result: A total of 29 articles were evaluated and selected according to the eligibility criteria. Conclusion: Infection of the surgical site is the most common postoperative complication. The key point of its prevention is the combination of several interventions that aim to reduce risk factors, such as: compliance with the new guidelines of the Center for Disease Control and Prevention; the principles of the use of prophylactic antibiotics; factors and risk index of the surgical site; administration time; duration and dosage of antibiotics. These data are available in this article.

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Section: Resultsmentioning

confidence: 99%

What’s New in Infection on Surgical Site and Antibioticoprophylaxis in Surgery?

Costa

Santa‐Cruz

Ferraz

2020

ABCD, arq. bras. cir. dig.

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“…Extensive data have established that the length of the residual small intestine and remaining ileocecal valve have significant effects on enteral autonomy ( 11 , 25 , 26 ). Consistent with the findings of previous studies, the results of the present study showed that a longer RSB or the presence of an ileocecal valve was associated with a greater likelihood of achieving enteral autonomy.…”

Section: Discussionmentioning

confidence: 99%

Multi-Center Analysis of Predictive Factors of Enteral Autonomy and Risk Factors of Complications of Pediatric Intestinal Failure in China

et al. 2022

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ObjectivesThe aim of this study was to identify predictors for enteral autonomy and intestinal failure (IF)-related complications and evaluate the outcomes of a multi-center pediatric cohort in China.MethodsThe medical records of pediatric patients with IF treated at four medical centers in China from January 1, 2012 to November 31, 2020 were retrospectively reviewed. Enteral autonomy was defined as sustained growth and cessation of parenteral nutrition for >90 days. Multivariate logistic regression analysis was used to identify factors predictive of enteral autonomy and the risk factors of complications, such as IF-associated liver disease (IFALD) and catheter-related bloodstream infection (CRBSI).ResultsThe study cohort of 92 pediatric patients with IF included 71 (77%) who underwent surgery and 21 (23%) who received non-surgical treatment. Eventually, 63 (68.5%) patients achieved enteral autonomy by the end of the follow-up period. Multivariate logistic regression analysis indicated that longer duration of parenteral nutrition (PN), sepsis, and non-breastfeeding were risk factors for enteral autonomy. When considering the detailed intraoperative data, the presence of an ileocecal valve (ICV) and greater residual small bowel (RSB) length were reaffirmed as predictors of achieving enteral autonomy. Medium/long-chain (MCT/LCT) lipids or sepsis were identified as negative predictors for IFALD. Univariate analysis revealed that the use of MCT/LCT lipids was associated with a greater likelihood of CRBSI.ConclusionIn this cohort, enteral autonomy was achieved at a percentage of 68.5%, and the risk factors for not achieving enteral autonomy were a longer duration of PN, sepsis, and non-breastfeeding. The presence of an ICV and a greater RSB length were important predictors of achieving enteral autonomy.

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“…Presence of the ileocecal valve slows down the ileal transit time allowing for more absorption. Besides; resection of the valve will colonize the small intestine with colon bacteria resulting in diarrhea [15].…”

Section: Discussionmentioning

confidence: 99%

Lessons learned from successful autologous gastrointestinal reconstruction in patients with intestinal failure: a case series

et al. 2021

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Background Intestinal failure (IF) is a rare but severe form of organ failure. The condition is defined as body’s inability to absorb adequate fluids, macronutrients and minerals for growth and development, so that intravenous supplementation is necessary. A broad spectrum of diseases, trauma and complications of surgery might eventually end up with intestinal failure. Nowadays, intestinal failure patients are preferably cared for in intestinal rehabilitation units (IRU). Autologous gastrointestinal reconstruction (AGIR) refers to non-transplant operative management of IF patients designed to improve enteral tolerance and gut absorptive capacity. Case presentation Herein we present five cases with complications of surgeries due to peptic ulcer bleeding, blunt abdominal trauma, obesity and gastric tumor. The surgeries were complicated by anastomotic leak, peritonitis and fistula formation. By adopting multidisciplinary decisions and special care for each complication, all the five patients were successfully managed and discharged. Discussion and conclusions As presented, re-anastomosis in presence of abdominal contamination will probably fail. In patients with intestinal failure, PN should start as soon as possible to increase the success rate of future surgeries and prevent potential need for intestinal transplantation. We suggest referring patients with complicated outcomes of gastrointestinal surgeries to the IRUs to reduce morbidity and mortality.

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The Effect of Ileocecal Valve Removal in a Model of Short Bowel Syndrome

Cited by 6 publications

References 15 publications

What’s New in Infection on Surgical Site and Antibioticoprophylaxis in Surgery?

What’s New in Infection on Surgical Site and Antibioticoprophylaxis in Surgery?

Multi-Center Analysis of Predictive Factors of Enteral Autonomy and Risk Factors of Complications of Pediatric Intestinal Failure in China

Lessons learned from successful autologous gastrointestinal reconstruction in patients with intestinal failure: a case series

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