Gastric Stump Cancer After Gastrectomy by Gastroduodenal Peptic Ulcer

Filho, Augusto Diogo; Botelho, Lucas Ferreira; Nishiyama, Andréa; Zumpano, Letícia Eugênia; Monte, Rosana Caldeira; Rosa, Samantha Cunha

doi:10.1590/0102-6720201600010017

Cited by 4 publications

(1 citation statement)

References 10 publications

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“…Frequently, GSC develops after distal gastrectomy performed for malignant tumors [4]. An influential role for this characteristic is attributed to the chronic treatment with proton pump inhibitors and anti-H2 therapy, which have led to a significant decline of surgical procedures for benign lesions [5]. Due to a lack of symptoms GSC is diagnosed in an advanced stage when few treatment resources are available and has a low resectability rate and a poor prognosis.…”

Section: Introductionmentioning

confidence: 99%

Gastric stump cancer. Etiology and treatment. A general review of the last 5 years

Braga¹,

Slavu²,

Tulin³

et al. 2019

JSS

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Introduction: Gastric stump cancer (GSC) is an entity described in the literature as early as the 1920s. Along the years the clinicopathological characteristic had changed. At the moment, there are no well-established guidelines regarding the optimal treatment. Material and method: We conducted a literature review of the studies published from 2014 to 2019 using the PubMed database. Results: After searching the PubMed database for the keywords: “gastric remnant cancer” AND “stump” AND “neoplasm” we identified 167 articles. Of these, 25 studies were considered relevant. Discussions: GSC develops after 2 years from the primary intervention for malignancy and after 20 years for benign lesions. The development mechanisms vary depending on the type of primary gastric lesions. GSC is considered a unique clinicopathological entity. The pattern of lymphatic drainage is different in comparison to primary gastric neoplasm. Thus an important negative prognostic factor is considered to be the N group of TNM staging. Conclusion: More studies are required to improve the understanding of development mechanisms and evolution of this pathology. Survival after gastric cancer has increased and it is possible to observe an increased percentage of patients who achieve the 5-year survival interval after surgery. Currently, there are no guidelines to select the optimal treatment with regards to surgery or chemotherapy as pathology is rare and studies which investigate the evolution and prognosis lack a significant cohort of patients. Therefore, the existent data is not substantial enough to elaborate guidelines that would define a standard surgical treatment.

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Section: Introductionmentioning

confidence: 99%

Gastric stump cancer. Etiology and treatment. A general review of the last 5 years

Braga¹,

Slavu²,

Tulin³

et al. 2019

JSS

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The option of surgery for gastric stump cancer in patients who have previously undergone pancreaticoduodenectomy

Akhmetzyanov

Шайхутдинович²,

Valiev³

et al. 2021

Kazan Med J

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Gastric stump cancer is a carcinoma which forms no earlier than 5years after surgery for benign disease. The incidence ranges from 2.4 to 5% among patients with stomach cancer. Previous operations lead to the emergence of an adhesive process in the abdominal cavity, changes in the anatomy and topography of the abdominal organs, as well as the development of new ways of lymph outflow. These factors lead to the re-surgery becomes technically more complicated and requires high professional training from the surgeon. Of particular surgical interest is the issue of restoration of the digestive tract, which directly depends on the nature and volume of the previous surgery. In this paper, the authors describe cases of surgical treatment of gastric stump cancer in two patients, who had previously undergone pancreaticoduodenectomy.

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