Mudanças no padrão de internações e óbitos por COVID-19 após substancial vacinação de idosos em Manaus, Amazonas, Brasil

Orellana, Jesem Douglas Yamall; Cunha, Geraldo Marcelo da; Marrero, Lihsieh; Leite, Iúri da Costa; Domingues, Carla Magda Allan Santos; Horta, Bernardo Lessa

doi:10.1590/0102-311xpt192321

Cited by 21 publications

(18 citation statements)

References 30 publications

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“…These data corroborate the findings of other studies, which showed a significant decline in the number of cases among the elderly accompanying the commencement of vaccination, with a consequent tendency for rejuvenation in hospitalizations and deaths [9][10][11] . Data from the Ministry of Health on COVID-19 showed that between the beginning of January and the end of June 2021 there was a reduction in the average age among hospitalized cases from 62.3 to 52.5 years old, and from 71.4 to 61.2 years old for deaths in Brazil 12 .…”

Section: Discussionsupporting

confidence: 91%

Hospitalizations for COVID-19 in a tertiary hospital in Brazil: a parallel with vaccination

Salomão

Machado

Fernandes

et al. 2022

Rev. Inst. Med. trop. S. Paulo

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This study aimed to evaluate the COVID-19 hospitalizations in a tertiary hospital by age group and month, considering the introduction and the advance of the vaccination against the disease. The laboratory-confirmed COVID-19-associated hospitalizations among people aged 20 years or older, that occurred between March 2020 and June 2021, were distributed by month of symptom onset and age group. The proportion of hospitalizations by age group was calculated for the year 2021. The proportions were compared using the chi-square test for trends. The marks of vaccination advances among different age groups were taken from the official website LocalizaSUS. In 2020, hospitalizations among people aged 60-80 years old were the most frequent (39.1%). From January-June 2021, when the vaccination commenced, while hospitalizations of patients aged 20 to < 40 and 40 to 60 years old showed an increasing trend, the older age groups and those with vaccination recommendations (from 60 to < 80 and from 80 or over) showed a downward trend. As of June 2021, with widespread vaccination, a drop in hospitalizations was observed in > 60 years old. At 20 to <40 and 40 to < 60, an increase in hospitalizations was observed. It demonstrates the important role of vaccination in combating the COVID-19 pandemic.

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Section: Discussionsupporting

confidence: 91%

Hospitalizations for COVID-19 in a tertiary hospital in Brazil: a parallel with vaccination

Salomão

Machado

Fernandes

et al. 2022

Rev. Inst. Med. trop. S. Paulo

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“…The other studies compare all groups of hospitalized patients. However, when it comes to the change in profile of the vaccinated hospitalized patients, studies have observed the change in pattern, as well as in young men with no comorbidities that were not vaccinated [59][60][61].…”

Section: Discussionmentioning

confidence: 99%

Clinical Characteristics and Outcomes among Vaccinated and Unvaccinated Patients with Cardiovascular Disease Who Were Hospitalized for COVID-19 in Brazil: Retrospective Cohort

et al. 2023

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Introduction: COVID-19 in Brazil has already caused, and it still causes, several impacts on health, economy, and education. The risk factors for death involved those with cardiovascular diseases (CVD), which were prioritized for the vaccination of COVID-19. Objective: To investigate the clinical characteristics and outcomes between vaccinated and unvaccinated patients with cardiovascular diseases hospitalized for COVID-19 in Brazil in the year 2022. Methods: A retrospective cohort was analyzed from the year 2022, with cases being hospitalized by COVID-19 being drawn from SIVEP-GRIPE surveillance. We compared clinical characteristics, comorbidities, and outcomes between CVD carriers and non-carriers, and we also compared vaccinated with two doses vs. those that are unvaccinated in CVD carriers. We performed chi-square, odds ratio, logistic regression, and survival analysis. Results: We included, in the cohort, 112,459 hospital inpatients. An amount of 71,661 (63.72%) of the hospitalized patients had CVD. Regarding deaths, 37,888 (33.69%) died. Regarding vaccination against COVID-19, 20,855 (18.54%) people were not vaccinated with any dose among those with CVD. Death p- < 0.001 (OR 1.307-CI 1.235–1.383) and fever p- < 0.001 (OR 1.156-CI 1.098–1.218) were associated with the unvaccinated CVD carriers, and diarrhea p-0.015 (OR 1.116-CI 1.022–1.218), dyspnea p-0.022 (OR 1.074-CI 1.011–1.142), and respiratory distress p-0.021 (OR 1.070-CI 1.011–1.134) were also recorded. Those patients who possessed predictors of death, including invasive ventilation (p- < 0.001 (OR 8.816-CI 8.313–9.350)), were admitted to the ICU p- < 0.001 (OR 1.754-CI 1.684–1.827), and some had respiratory distress p- < 0.001 (OR 1.367-CI 1.312–1.423), dyspnea p < 0.001 (OR 1.341-CI 1.284–1.400), O2 saturation < 95% p- < 0. 001 (OR 1.307-CI 1.254–1.363), they were unvaccinated against COVID-19 p- < 0.001 (OR 1.258-CI 1.200–1.319), they were of male sex p- < 0.001 (OR 1.179-CI 1.138–1.221), they had diarrhea p-0.018 (OR 1.081-CI 1.013–1.154), and they may have been old p < 0.001 (OR 1.034-CI 1.033–1.035). Survival was shorter for the unvaccinated p-0.003, and p- <0.001. Conclusions: We highlight the predictors of death for those unvaccinated against COVID-19 in this research, and we evidenced the benefits of the COVID-19 vaccine in reducing deaths in hospitalized CVD patients.

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“…Este cenário acarretou um sistema de saúde nacional próximo ao colapso (Brasil, 2020). A partir de 2021, com a chegada da imunização contra a COVID-19, observou-se a redução da mortalidade geral da população, e esta foi recomendada, no mundo todo, para gestantes e puérperas (Orellana et al, 2022). Neste contexto, o distanciamento social, a imunização para a doença, o uso de máscara e outras medidas, se tornaram as principais formas de proteção para esta população (Brasil, 2021).…”

Section: Introductionunclassified

Conhecimento e percepção de gestantes sobre a COVID-19: impacto nas práticas de cuidado no pré-natal

Santos

Day²,

Lanzarini³

et al. 2023

RSD

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Objetivo: compreender como os conhecimentos e as percepções de gestantes sobre a COVID-19 influenciam suas práticas de cuidado. Métodos: Estudo qualitativo, descritivo-exploratório, com gestantes no 3º trimestre, com 18 anos ou mais e que realizaram pré-natal em uma Unidade de Saúde de Porto Alegre/RS, os dados foram coletados por contato telefônico, através de entrevista semiestruturada. Foi realizada análise de conteúdo. A pesquisa foi aprovada no Comitê de Ética em Pesquisa da do Grupo Hospitalar Conceição (GHC). Resultados: Emergiram três categorias: conhecimento sobre o novo coronavírus, Práticas de cuidado realizadas pelas gestantes frente à pandemia e Sentimentos da pandemia. Considerações finais: Evidenciou-se que as gestantes enfrentam desafios frente aos impactos econômicos do isolamento social e da preocupação com o recém-nascido. Assim, a continuidade do pré-natal torna-se fundamental no contexto da pandemia.

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Mudanças no padrão de internações e óbitos por COVID-19 após substancial vacinação de idosos em Manaus, Amazonas, Brasil

Cited by 21 publications

References 30 publications

Hospitalizations for COVID-19 in a tertiary hospital in Brazil: a parallel with vaccination

Hospitalizations for COVID-19 in a tertiary hospital in Brazil: a parallel with vaccination

Clinical Characteristics and Outcomes among Vaccinated and Unvaccinated Patients with Cardiovascular Disease Who Were Hospitalized for COVID-19 in Brazil: Retrospective Cohort

Conhecimento e percepção de gestantes sobre a COVID-19: impacto nas práticas de cuidado no pré-natal

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