2016
DOI: 10.1590/0102-311x00080515
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Abstract: Diarrhea by rotavirus is one of the main causes of mortality in children in developing countries, although the hospitalization rates (HR) for acute diarrhea have been found to have fallen since the introduction of the rotavirus vaccine. However, the patterns of the rotavirus are still not well understood and seasonal peaks occur throughout the year, with variations between countries and over time. The main objective of this study was to analyze the temporal behavior of HR caused by acute diarrhea in children u… Show more

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Cited by 6 publications
(3 citation statements)
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“…Recent studies also suggest rotavirus seasonality might be weaker in the tropics, with some evidence that it peaks during the cooler and drier seasons [4–6, 26]. Introduction of rotavirus vaccine may attenuate the annual peaks in diarrheal disease associated with rotavirus [27]. We found less consistent periodicity of other pathogens across GEMS sites; however, there is less evidence in the scientific literature on the global seasonality of diarrheal pathogens other than rotavirus.…”
Section: Discussionmentioning
confidence: 62%
“…Recent studies also suggest rotavirus seasonality might be weaker in the tropics, with some evidence that it peaks during the cooler and drier seasons [4–6, 26]. Introduction of rotavirus vaccine may attenuate the annual peaks in diarrheal disease associated with rotavirus [27]. We found less consistent periodicity of other pathogens across GEMS sites; however, there is less evidence in the scientific literature on the global seasonality of diarrheal pathogens other than rotavirus.…”
Section: Discussionmentioning
confidence: 62%
“…We will compare these findings with the post-vaccination variations. We expect changes in seasonal patterns after universal vaccine implementation, including delays in the start of rotavirus season, shorter duration of seasons and blunting of seasonal peaks [35,36,37,38]. The presented model for estimating the peak timing will allow us to monitor changes in disease incidence.…”
Section: Discussionmentioning
confidence: 99%
“…Millions of people have suffered from diseases such as diarrhea, especially children, and this disease is one of the main causes of morbidity and mortality among children, especially in the group aged zero to four full years [ 9 , 11 , 14 ]. Most cases (50%) are caused by rotavirus in several countries [ 15 , 33 ], despite increased vaccination coverage, improved health conditions and knowledge about oral rehydration [ 5 , 9 ]. In Brazil, children aged up to 5 years are the most affected and 80% are younger than 1 year old [ 14 , 17 ], especially in the North region, where diarrheal diseases rank 8th in the causes of infant mortality [ 18 ].…”
Section: Discussionmentioning
confidence: 99%