2022
DOI: 10.1590/0102-311x00061521
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Abstract: The NEPHROS is a randomized controlled trial which applied a 16-week aerobic and resistance training to patients with chronic kidney disease (CKD) and high blood pressure. This report describes a long-term post-trial follow-up, comparing survival, health-related quality of life (HRQoL), and estimated glomerular filtration rate (GFR) change between the intervention and control groups according to in-trial cardiovascular risk factors. Three years after the original trial, NEPHROS participants were re-evaluated. … Show more

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Cited by 2 publications
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“…Considering the long-term response to exercise, no effects on GFR were observed following a 16-week exercise program in patients with hypertension and CKD but not with PAD. Interestingly, lower ABI together with lower eGFR and higher systolic blood pressure were associated with decreased survival [ 43 ]. In the present study, where the population was older, with PAD, and introduced to low-intensity exercise for a longer period, a relatively stable renal function in terms of sCr and eGFR was observed in EX, unlike the usual care group, where a progressive negative evolution occurred after 12 months.…”
Section: Discussionmentioning
confidence: 99%
“…Considering the long-term response to exercise, no effects on GFR were observed following a 16-week exercise program in patients with hypertension and CKD but not with PAD. Interestingly, lower ABI together with lower eGFR and higher systolic blood pressure were associated with decreased survival [ 43 ]. In the present study, where the population was older, with PAD, and introduced to low-intensity exercise for a longer period, a relatively stable renal function in terms of sCr and eGFR was observed in EX, unlike the usual care group, where a progressive negative evolution occurred after 12 months.…”
Section: Discussionmentioning
confidence: 99%