2020
DOI: 10.1590/0102-311x00049719
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Abstract: The Hospital of the Ribeirão Preto Medical School, University of São Paulo is one of the three screening centers in São Paulo State, Brazil, and has included a test for cystic fibrosis (CF) since February 6, 2010, by a court order. We evaluated the first five years of this CF-newborn screening program. The original immunoreactive trypsinogen (IRT)/IRT screening protocol was adopted in Brazil. A total of 173,571 newborns were screened, 1,922 (1.1%) of whom showed IRT1 ≥ 70ng/mL. Of these, 1,795 (93.4%) collecte… Show more

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Cited by 1 publication
(2 citation statements)
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“…18 , 19 Compared to the present study, however, the number of infants undergoing IRT2 following a successful active search was higher (93.4%) in São Paulo, highlighting the importance of improving follow-up in Bahia. 17 Nonetheless, the median of 7 days between delivery of IRT1 results and sampling for IRT2 was satisfactory and smaller than that reported in a study in Rio Grande do Sul where the median time until attendance for IRT2 was 18 days. 20 In the present study, the median age of the infants at referral to the treatment center (44 days) was less than in other states such as Piauí (56 days) and Rio de Janeiro (48 days).…”
Section: Discussioncontrasting
confidence: 67%
See 1 more Smart Citation
“…18 , 19 Compared to the present study, however, the number of infants undergoing IRT2 following a successful active search was higher (93.4%) in São Paulo, highlighting the importance of improving follow-up in Bahia. 17 Nonetheless, the median of 7 days between delivery of IRT1 results and sampling for IRT2 was satisfactory and smaller than that reported in a study in Rio Grande do Sul where the median time until attendance for IRT2 was 18 days. 20 In the present study, the median age of the infants at referral to the treatment center (44 days) was less than in other states such as Piauí (56 days) and Rio de Janeiro (48 days).…”
Section: Discussioncontrasting
confidence: 67%
“…In this study, the median age of infants at sampling for IRT1 in Bahia was lower than in other Brazilian states. 17 , 18 Despite the complexity involved in providing newborn CF screening in a large, populous state, the percentage of samples collected before 7 days of life exceeded the rates reported for Rio de Janeiro (38.3%) and Piauí (36.8%). 18 , 19 The median time interval between collection and the sample being received at the laboratory was like that reported for Rio de Janeiro (8 days) and Piauí (5 days).…”
Section: Discussionmentioning
confidence: 94%