2013
DOI: 10.1590/0074-0276108062013009
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Abstract: Intrathecal synthesis of human T-lymphotropic virus type 1 (HTLV-1) antibodies (Abs) represents conclusive evidence of a specific immune response in the central nervous system of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients. Western blotting (WB) for HTLV Abs in serum is a confirmatory test for HTLV-1 infection. The aim of this study was to standardise the Western blot to demonstrate the intrathecal pattern of Abs against HTLV-1 proteins in HAM/TSP patients. Paired cerebrospinal… Show more

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Cited by 3 publications
(1 citation statement)
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“…While it is clear that abs against specific HLTV-1 proteins can be detected in HAM/TSP patients and at higher levels than in ACs (Kitze et al, 1996, the role HTLV-1 specific antibodies could play in pathogenesis is unclear. Some postulate that HTLV-1 specific abs in the CSF are in fact detrimental (Ribeiro et al, 2013). …”
Section: Staining Of T Cells Post-exosome Exposurementioning
confidence: 99%
“…While it is clear that abs against specific HLTV-1 proteins can be detected in HAM/TSP patients and at higher levels than in ACs (Kitze et al, 1996, the role HTLV-1 specific antibodies could play in pathogenesis is unclear. Some postulate that HTLV-1 specific abs in the CSF are in fact detrimental (Ribeiro et al, 2013). …”
Section: Staining Of T Cells Post-exosome Exposurementioning
confidence: 99%