Executive functions and emotion regulation in substance use disorder

Background Substance abuse is a major health problem, associated with multiple clinical correlates. Cognitive dysfunctions were among the most relevant health problems associated with substance abuse among adolescents. The aim of the study is investigate the main cognitive domains affected in a sample of adolescents with substance use disorders. A case-control comparison was performed between 100 substance abusers versus 40 controls. The Mini-International Neuropsychiatric Interview v.5, Addiction Severity Index, Wisconsin Card Sorting Test, socioeconomic scale, and multiple historical variables investigated. Results Substance abusers showed higher mean than control as regard all other WCST domains. The difference between two groups was statistically significant. Cannabis substance mostly affects early conceptualization and problem-solving abilities, while inhalants affect predominantly sustained attention, and alcohol mostly affect cognitive flexibility. Polysubstance use is more harmful to most of the executive function domain than mono substance use. Conclusions The substance use disorders are a major health problem accompanied cognitive dysfunction among adolescents and associated with increased rates of executive dysfunction. Cognitive flexibility, sustained attention, problem-solving abilities, and early conceptualization are the most domains affected.

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Cognitive dysfunction in adolescents with substance use disorder

Abdulaal

Tantawy

Ibrahim

et al. 2023

Middle East Curr Psychiatry

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The relationship between childhood maltreatment and social anxiety among Chinese male individuals with drug use disorders: a moderated mediation model of fear of negative evaluation and self-construals

Liu,

Zhang,

Miao

et al. 2023

Front. Psychol.

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BackgroundSocial anxiety (SA) is prevalent among individuals with drug use disorders, playing a significant role in the etiology and maintenance of drug addiction. The etiological model of SA suggests a link between the development of SA and childhood maltreatment. Childhood maltreatment not only acts as a complex trauma with negative effects on individuals’ selves and other cognitions but also exerts a negative influence through early negative parent–child interactions on individuals’ internal working models, leading to the development of fear of negative evaluation and SA. Furthermore, self-construals, as a personality trait that emerges from the framework of the theory of sociocultural models, may exert a moderating effect on these mechanisms. The present study utilized a moderated mediation model to examine how childhood maltreatment relates to SA in individuals with drug addiction, aiming to provide support for a comprehensive understanding and effective resolution of SA in this group.MethodsA total of 618 Chinese male individuals with drug addiction (M = 34.13, SD = 8.76) participated, and they completed the Childhood Trauma Questionnaire Short Form, the Fear of Negative Evaluation Scale, the Self-Consciousness Scale’s Social Anxiety Subscale, and the Self-Construal Scale. SPSS PROCESS Macro was used to analyze the data.ResultCorrelation analysis revealed weak correlations among all variables but strong correlations between the SCS subscales. Mediation analyses revealed that fear of negative evaluation partially mediated the association between childhood maltreatment and SA. Moderated mediation analyses revealed that the link between fear of negative evaluation and SA was moderated by independent self-construal. The association was stronger among those with high independent self-construal than among those with low independent self-construal. An integrative moderated mediation analysis indicated that independent self-construal positively moderated the indirect association between childhood maltreatment and SA via fear of negative evaluation. However, interdependent self-construal did not show a moderated effect.ConclusionFear of negative evaluation plays a partial mediating role in the relationship between childhood maltreatment and SA, while independent self-construal enhances the association between fear of negative evaluation and SA. Decreasing the fear of negative evaluation and intervening in self-construals may attenuate the association between childhood maltreatment and SA among Chinese male individuals with drug addiction.

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Executive functions and emotion regulation in substance use disorder

Cited by 2 publications

References 49 publications

Cognitive dysfunction in adolescents with substance use disorder

Cognitive dysfunction in adolescents with substance use disorder

The relationship between childhood maltreatment and social anxiety among Chinese male individuals with drug use disorders: a moderated mediation model of fear of negative evaluation and self-construals

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