Reassessment of quality of life domains in patients with compensated Chagas heart failure after participating in a cardiac rehabilitation program

Mediano, Mauro Felippe Felix; Mendes, Fernanda de Souza Nogueira Sardinha; Pinto, Vítor Laerte; Silva, Paula Simplício da; Hasslocher‐Moreno, Alejandro Marcel; Sousa, Andréa Silvestre de

doi:10.1590/0037-8682-0429-2016

Cited by 18 publications

(21 citation statements)

References 12 publications

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“…Therefore, we can suggest that physically active individuals could maintain sufficient levels of mobility and independence that positively influenced the perception of QoL in this domain. Thus, physical activity programs for patients with CD should be encouraged whenever individuals do not present medical restrictions .…”

Section: Discussionmentioning

confidence: 99%

Quality of life and associated factors in patients with chronic Chagas disease

Santos-Filho

Vieira

Xavier

et al. 2018

Tropical Med Int Health

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Section: Discussionmentioning

confidence: 99%

Quality of life and associated factors in patients with chronic Chagas disease

Santos-Filho

Vieira

Xavier

et al. 2018

Tropical Med Int Health

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“…A previous study found that heart rate (beats per minute) in T. cruzi experimentally infected dogs was significantly higher than control dogs during acute infection, but no difference was found during the indeterminate phase [33]. Chronic Chagas cardiomyopathy in humans can cause a decreased response to exercise and stress due to failure of cardiac compensation [61,62]. However, benefits of exercise training in chronic heart failure patients has been shown, and new research suggests that regular exercise could assist with cardiac function in chronic Chagas disease in humans [63,64].…”

Section: Discussionmentioning

confidence: 99%

Selected cardiac abnormalities in Trypanosoma cruzi serologically positive, discordant, and negative working dogs along the Texas-Mexico border

et al. 2020

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Background: Chagas disease is increasingly recognized in the southern U.S., where triatomine vectors transmit Trypanosoma cruzi among wildlife and domestic dogs with occasional vector spillover to humans. As in humans, clinical outcome in dogs is variable, ranging from acute death to asymptomatic infections or chronic heart disease. In order to characterize cardiac manifestations of T. cruzi infections, we tracked a cohort of naturally-infected dogs and a matched cohort of uninfected dogs. We hypothesized that selected measures of cardiac disease (abnormal rate, abnormal rhythm, and elevated cardiac troponin I (cTnI; a biomarker of cardiac injury)) would occur more commonly in infected than uninfected dogs matched by age, breed, sex and location. In addition to the clearly positive and negative dogs, we specifically tracked dogs with discordant test results across three independent serological assays to gather clinical data that might elucidate the infection status of these animals and inform the utility of the different testing approaches. Results: We placed an ambulatory ECG monitor (Holter) on 48 government working dogs and analyzed 39 successful recordings that met length and quality criteria from 17 T. cruzi-infected, 18 uninfected dogs and 4 dogs with discordant results. Overall, 76.5% of positive, 100.0% of discordant, and 11.1% of negative dogs showed > 1 ECG abnormality (p < 0.0001), and positive and discordant dogs had a higher mean number of different types of ECG abnormalities than negative dogs (p < 0.001-0.014). The most common cardiac abnormalities included supraventricular and ventricular arrhythmias and atrioventricular block. Positive dogs had higher serum concentrations of cTnI than both negative dogs (p = 0.044) and discordant dogs (p = 0.06). Based on dog handler reports, nearly all (4/5; 80%) dogs with reported performance decline or fatigue were T. cruzi-infected dogs.Conclusions: Further understanding cardiac manifestations in dogs naturally infected with T. cruzi is critical for prognostication, establishing a baseline for drug and vaccine studies, and better understanding of zoonotic risk.

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“…30 Um programa de reabilitação cardíaca composto do mesmo protocolo de TEF mencionado acima, com TR e alongamentos, orientação nutricional adicional e aconselhamento farmacológico para pacientes com DC, demonstrou aumento da capacidade funcional e física, melhorando a qualidade de vida de pacientes chagásicos. 31 Em outro estudo importante, os pesquisadores realizaram TEF três vezes por semana em pacientes chagásicos. Eles demonstraram que o grupo que realizou exercícios aumentou o consumo de oxigênio de pico durante o exercício e a ventilação máxima por minuto, melhorando a capacidade funcional desses pacientes.…”

Section: Doença De Chagas E Treinamento Com Exercício Físico: Mirnas Como Possíveis Moduladoresunclassified

Treinamento com Exercício Físico e Doença de Chagas: Função Potencial dos MicroRNAs

Improta-Caria

Júnior

2021

Arquivos Brasileiros De Cardiologia

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Reassessment of quality of life domains in patients with compensated Chagas heart failure after participating in a cardiac rehabilitation program

Abstract: The cardiac rehabilitation program significantly improved the physical quality of life of patients with Chagas heart failure.

Cited by 18 publications

References 12 publications

Quality of life and associated factors in patients with chronic Chagas disease

Quality of life and associated factors in patients with chronic Chagas disease

Selected cardiac abnormalities in Trypanosoma cruzi serologically positive, discordant, and negative working dogs along the Texas-Mexico border

Treinamento com Exercício Físico e Doença de Chagas: Função Potencial dos MicroRNAs

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