2018
DOI: 10.1590/0037-8682-0216-2017
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Abstract: Corticosteroid or thalidomide adverse effects and aPL and ß2GPI polymorphisms may cause TBE in patients with MB leprosy.

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Cited by 4 publications
(4 citation statements)
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“…It must be noted, that in the absence of routine assessment for ruling out thrombophilia, introducing aspirin (100 mg/day) was part of an existing recommendation for treating ENL. [ 41 ] So IADVL SIG leprosy recommends the addition of low-dose aspirin and timely initiation of antithrombotic therapy in COVID-19 positive leprosy cases considering the risk factors like steroid or thalidomide use, obesity, diabetes, and in nonambulatory patients. ( Level of Evidence VII )…”
Section: Introductionmentioning
confidence: 99%
“…It must be noted, that in the absence of routine assessment for ruling out thrombophilia, introducing aspirin (100 mg/day) was part of an existing recommendation for treating ENL. [ 41 ] So IADVL SIG leprosy recommends the addition of low-dose aspirin and timely initiation of antithrombotic therapy in COVID-19 positive leprosy cases considering the risk factors like steroid or thalidomide use, obesity, diabetes, and in nonambulatory patients. ( Level of Evidence VII )…”
Section: Introductionmentioning
confidence: 99%
“…4 Although these antibodies are not believed to be pathogenic, it was reported in a recent series that 7 patients with multibacillary leprosy (5 of which were receiving concomitant thalidomide and prednisolone) developed significant thrombotic events. 5 All of them were positive for APLAs and the anti-beta-2-glycoprotein polymorphism. 5 In light of this study, the Brazilian government has mandated the addition of low-dose aspirin with thalidomide while treating ENL.…”
mentioning
confidence: 96%
“…5 All of them were positive for APLAs and the anti-beta-2-glycoprotein polymorphism. 5 In light of this study, the Brazilian government has mandated the addition of low-dose aspirin with thalidomide while treating ENL. 5 The risk for thrombosis with thalidomide is established in the hematologic literature.…”
mentioning
confidence: 96%
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