Prevalence of and risk factors associated with the presence of Staphylococcus aureus in the chronic wounds of patients treated in primary health care settings in Brazil

Abstract

Introduction: Wounds can be colonized by methicillin-resistant Staphylococcus aureus (MRSA). Methods: We evaluated the prevalence of S. aureus and MRSA in the wounds of patients treated at Basic Health Units in Brazil and identifi ed risk factors associated with their presence. Results: The prevalence rates of S. aureus and MRSA were 51.5% and 8.7%, respectively. There was a correlation between the presence of S. aureus in wounds and nostrils (p<0.01). A positive association was detected between S. aureus infection and previous benzylpenicillin use (p=0.02). No associations were observed for MRSA. Conclusions: Multidrug-resistant pathogens are present in primary healthcare settings in Brazil.

Prevalence and Risk Factors for Nasal and Oropharyngeal Carriage of Staphylococcus Aureus in Insulin-Dependent Diabetics Individuals

“…Multivariate analysis identi ed male gender as a risk factor for colonization with MRSA. These results are in contrast with those reported by Pereira-Franchi et al [36] who found no risk factors for MRSA colonization.…”

“…Age was negatively associated with S. aureus colonization, with an odds ratio of 0.98, indicating a reduction of 2% in the risk of colonization for each additional year of age. Similar data have been reported by Pereira-Franchi et al [36] Lung disease was also negatively associated with S. aureus colonization, a fact that might be related to colonization of the respiratory tract by other microorganisms that are competing with S. aureus. Mueller et al [37] also found a negative association with age but, in contrast to our ndings, lung disease was a risk factor for S. aureus colonization.…”

Molecular epidemiology of methicillin‐resistant Staphylococcus aureus in the Brazilian primary health care system

“…Benzylpenicillin was one of the drugs most patients reported using within one year. The analysis of risk factors obtained in our previous results identified a positive association between the use of benzylpenicillin and the presence of S. aureus ( P = 0.02) , this is one of the most commonly used drugs in primary care.…”

“…We also performed the drug susceptibility tests in these isolates and the results were previously published . The results showed that among the 119 S. aureus isolates, most were resistant to penicillin [ n = 101 (85%)], followed by erythromycin [ n = 32 (27%)], gentamicin [ n = 14 (12%)], clindamycin [ n = 13 (11%)] and levofloxacin [ n = 7 (6%)].…”

“…We also performed the drug susceptibility tests in these isolates and the results were previously published [37]. The results showed that among the 119 S. aureus isolates, most were resistant to penicillin [n = 101 (85%)], at least six antibiotics, and type IV to at least three antibiotics.…”