2014
DOI: 10.1590/0037-8682-0137-2013
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Effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers

Abstract: Introduction:The aim of this study was to investigate the effects of Rosmarinus offi cinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers. Methods: Ten C. albicans isolates recovered from denture wearers were tested using 10% fetal bovine serum with or without 4% R. offi cinalis essential oil. Results: The essential oil from R. offi cinalis completely inhibited germ tube formation in the investigated C. albicans isolates. Conclusions: The results demonstrate that the e… Show more

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Cited by 17 publications
(9 citation statements)
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“…Additionally, the antifungal activity of R. officinalis L. essential oil has been related to the inhibition of C. albicans germ tube formation, an important virulence factor used for penetration and diffusion in organic tissues [110]. This effect occurs due to oxidative stress generated by the plant product, which triggers alterations in enzymatic activity and potential of mitochondrial cell membrane.…”
Section: Mono- and Polymicrobial Biofilms Reductionmentioning
confidence: 99%
“…Additionally, the antifungal activity of R. officinalis L. essential oil has been related to the inhibition of C. albicans germ tube formation, an important virulence factor used for penetration and diffusion in organic tissues [110]. This effect occurs due to oxidative stress generated by the plant product, which triggers alterations in enzymatic activity and potential of mitochondrial cell membrane.…”
Section: Mono- and Polymicrobial Biofilms Reductionmentioning
confidence: 99%
“…Em se tratando dos achados referentes às infeções fúngicas proposto por Gauch et al 27 , o R. officinalis L. apresentou capacidade de interferir na filamentação in vitro de amostras clínicas de C. albicans, através de um importante fator de virulência desta levedura. A avaliação foi conduzida com C. albicans provenientes de próteses dentárias.…”
Section: O Constituintes Químicos Rosmarinus Officinalis Lunclassified
“…In addition, some data indicate that the essential oil of Rosmarinus officinalis (Fam. Lamiaceae) modulates C. albicans pathogenicity through its primary virulence factor, which is the suppression of germ tube formation (Gauch et al, 2014).…”
Section: Essential Oilsmentioning
confidence: 99%