2015
DOI: 10.1590/0037-8682-0068-2015
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Abstract: Introduction:The human T-lymphotropic virus-1 (HTLV-1) is associated with chronic infl ammatory diseases such as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a chronic infl ammatory disease. Disturbances in lipid metabolism are involved in infl ammatory and demyelinating diseases. Methods: Plasma levels of triglycerides, total cholesterol, and fractions of HTLV-1-infected individuals of both sexes with different clinical progressions were determined. Results: Elevated levels of triglyce… Show more

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Cited by 5 publications
(6 citation statements)
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“…Lipoproteins have been found enriched, when compared to control donors. This is reminiscent of a previous study that found elevated levels of triglyceride and very low-density lipoproteins (VLDL) in HTLV-1 infected women compared with uninfected individuals 15 . Our cohort is mostly composed of female donors.…”
Section: Discussionsupporting
confidence: 66%
“…Lipoproteins have been found enriched, when compared to control donors. This is reminiscent of a previous study that found elevated levels of triglyceride and very low-density lipoproteins (VLDL) in HTLV-1 infected women compared with uninfected individuals 15 . Our cohort is mostly composed of female donors.…”
Section: Discussionsupporting
confidence: 66%
“…These data are in consistent with prior cross-sectional studies that did not demonstrate consistent associations between traditional cardiovascular risk factors [34], lipid levels, and HTLV serostatus [22]. In a study that evaluated lipid alterations in women infected with HTLV1, increased levels of very lowdensity lipoproteins and triglyceride were found in the women with HTLV1 and HAM/TSP groups as compared with healthy subjects [35]. Thus, changes in function of HDL rather than alterations in the levels of serum lipids and HDL-C may be a better predictor of CVD in chronic HTLV infection.…”
Section: Discussionsupporting
confidence: 91%
“…In a study that evaluated lipid alterations in women infected with HTLV1, increased levels of very low-density lipoproteins and triglyceride were found in the women with HTLV1 and HAM/TSP groups as compared with healthy subjects [35]. Thus, changes in function of HDL rather than alterations in the levels of serum lipids and HDL-C may be a better predictor of CVD in chronic HTLV infection.…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, it is concluded that HTLV1 infection by induction of systemic inflammation results in an altered level of lipid peroxidation (Samadi et al, 2019 ). Carvalho et al ( 2015 ) have shown that infection with HTLV1 in women is associated with increased serum triglyceride and very‐low‐density lipoprotein (VLDL) levels. They also introduced viral infections, increased lipid profiles through receptor engagement, and applied them as a defensive mechanism.…”
Section: Discussionmentioning
confidence: 99%