Temporal distribution of tuberculosis in the State of Amazonas, Brazil

Garrido, Marlucia da Silva; Bührer-Sékula, Samira; Souza, Alexandra B.; Ramasawmy, Rajendranath; Quincó, Patrícia de Lima; Monte, Rossicléia Lins; Santos, Lucilaide Oliveira; Perez-Porcuna, Tomas M; Martínez-Espinosa, Flor Ernestina; Saraceni, Valéria; Cordeiro-Santos, Marcelo

doi:10.1590/0037-8682-0055-2014

Cited by 12 publications

(16 citation statements)

References 9 publications

(10 reference statements)

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“…However, the incidence of tuberculosis-HIV co-infection was high in females, indicating a greater number of new HIV-positive women. These data support those of other studies conducted in Brazil that showed a higher incidence and prevalence of tuberculosis and HIV infection in males, as well as increased rates of tuberculosis-HIV co-infection, 3 , 14 which is influenced by genetic, environmental, and immunological factors and of which better understanding would lead to advances in diagnosis that would favor the development of new technologies and treatments for both diseases 15 …”

Section: Discussionsupporting

confidence: 87%

Temporal analysis of reported cases of tuberculosis and of tuberculosis-HIV co-infection in Brazil between 2002 and 2012

Gaspar¹,

Nunes

et al. 2016

J. bras. pneumol.

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Objective: To investigate the reported cases of tuberculosis and of tuberculosis-HIV co-infection in Brazil between 2002 and 2012. Methods: This was an observational study based on secondary time series data collected from the Brazilian Case Registry Database for the 2002-2012 period. The incidence of tuberculosis was stratified by gender, age group, geographical region, and outcome, as was that of tuberculosis-HIV co-infection. Results: Nationally, the incidence of tuberculosis declined by 18%, whereas that of tuberculosis-HIV co-infection increased by 3.8%. There was an overall decrease in the incidence of tuberculosis, despite a significant increase in that of tuberculosis-HIV co-infection in women. The incidence of tuberculosis decreased only in the 0-to 9-year age bracket, remaining stable or increasing in the other age groups. The incidence of tuberculosis-HIV co-infection increased by 209% in the ≥ 60-year age bracket. The incidence of tuberculosis decreased in all geographical regions except the south, whereas that of tuberculosis-HIV co-infection increased by over 150% in the north and northeast. Regarding the outcomes, patients with tuberculosis-HIV coinfection, in comparison with patients infected with tuberculosis only, had a 48% lower chance of cure, a 50% greater risk of treatment nonadherence, and a 94% greater risk of death from tuberculosis. Conclusions: Our study shows that tuberculosis continues to be a relevant public health issue in Brazil, because the goals for the control and cure of the disease have yet to be achieved. In addition, the sharp increase in the incidence of tuberculosis-HIV co-infection in women, in the elderly, and in the northern/northeastern region reveals that the population of HIV-infected individuals is rapidly becoming more female, older, and more impoverished.

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Section: Discussionsupporting

confidence: 87%

Temporal analysis of reported cases of tuberculosis and of tuberculosis-HIV co-infection in Brazil between 2002 and 2012

Gaspar¹,

Nunes

et al. 2016

J. bras. pneumol.

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“…A região Norte do Brasil é considerada zona endêmica de doenças infectocontagiosas, como hanseníase, síndrome da imunodeficiência humana adquirida (AIDS), leishmaniose, malária, leptospirose, tuberculose e hepatite 7,8,9,10,11,12,13,14 . E, ainda, configura local de doenças reemergentes como cólera e febre tifoide 12,15 .…”

Section: Introductionunclassified

Meningite: Aspectos Epidemiológicos Da Doença Na Região Norte Do Brasil

Dias¹,

Rodrigues²,

Cardoso³

et al. 2017

Rev Pat Tocantins

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A região Norte do Brasil é considerada zona endêmica de diversas doenças infectocontagiosas, das quais podemos citar a meningite. A doença possui diversos fatores causais, sendo que a etiologia viral é a mais comum, porém a de origem bacteriana apresenta-se como responsável pela maior taxa de mortalidade. Entretanto, apesar da sua relevância no contexto de saúde pública na região Norte do país, poucos são os estudos publicados sobre a meningite na região. Nesse sentido, foi realizado um estudo transversal com o objetivo de traçar o perfil dos indivíduos acometidos por essa doença no Norte do Brasil entre os anos de 2012 e 2015. Os dados foram obtidos no banco de dados oficial do Sistema de Informação de Agravos de Notificação (SINAN). No período de estudo, ocorreu queda no número de casos notificados, houve predominância do sexo masculino, da faixa etária entre 0 e 19 anos e de etiologia bacteriana. Este trabalho, associado a estimativas globais, pode fornecer subsídios para ações de prevenção e controle da meningite na região Norte. Palavras-chave: Meningite; Região Norte; Brasil; Epidemiologia. ABSTRACT Northern region of Brazil is considered an endemic area of several infectious diseases, such as meningitis. The disease has several causal factors, and the viral etiology is the most common, but the bacterial origin is responsible for the highest mortality rate. However, despite its relevance in the context of public health in the northern region of the country, there are a few published studies on meningitis in the region. So, a cross-sectional study was carried out with the objective of tracing the profile of the individuals affected by this disease in Northern Brazil between the years of 2012 and 2015. Data were collected from the official database of the notification of injury information system. During the study period, there was a decrease in the number of cases reported, there was a predominance of males, ages ranging from 0 to 19 years and bacterial etiology. This work, combined with global estimates, can provide subsidies for prevention and control of meningitis in the North. Keywords: Meningitis; Northern Brazil; Epidemiology.

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“…Tuberculosis remains a major challenge in the region and the historical series analyzed by Garrido et al (14) clearly shows a high mortality rate and a poor performance of the indicators of treatment success, which are affected by specific problems faced by the indigenous population and the growing human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) epidemic of. The main concern is the emergence of multidrug resistant M. tuberculosis, especially considering the frequent lack of access to timely diagnosis coupled with a high rate of noncompliance with treatment (14) .…”

Section: Conflict Of Interestmentioning

confidence: 99%

“…The main concern is the emergence of multidrug resistant M. tuberculosis, especially considering the frequent lack of access to timely diagnosis coupled with a high rate of noncompliance with treatment (14) .…”

Section: Conflict Of Interestmentioning

confidence: 99%