2017
DOI: 10.1590/0037-8682-0014-2017
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Abstract: Introduction:The control of reservoirs for Leishmania infantum-induced zoonotic visceral leishmaniasis requires the identification of dogs posing a population risk. Here, we assessed the performance of several assays to identify Lutzomyia longipalpis infectious dogs. Methods: We evaluated 99 dogs that were positive for visceral leishmaniasis based on parasite identification. Serological analyses were performed using an enzyme-linked immunosorbent assay, immunofluorescence antibody tests in 1:40 and 1:80 diluti… Show more

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Cited by 15 publications
(15 citation statements)
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“…Most of the seropositive dogs were symptomatic, which is consistent with the findings of Mendonça et al (2017). DPP  test sensitivity is known to be higher in symptomatic dogs (Grimaldi Junior et al 2012).…”
Section: Discussionsupporting
confidence: 84%
“…Most of the seropositive dogs were symptomatic, which is consistent with the findings of Mendonça et al (2017). DPP  test sensitivity is known to be higher in symptomatic dogs (Grimaldi Junior et al 2012).…”
Section: Discussionsupporting
confidence: 84%
“…In fact, Phlebotomus perniciosus and Lutzomyia longipalpis, proven vectors of L. infantum, were found infected after feeding respectively on one single sick cat with FeL (da Silva et al, 2010;Maroli et al, 2007). This is an important information but infectivity to sand flies of infected healthy individuals, as demonstrated in dogs, could be epidemiologically more relevant as the percentage of antibody and/or PCR positive cats is often not negligible in endemic areas (Akhtardanesh et al, 2017;Can et al, 2016;Chatzis et al, 2014aChatzis et al, , 2014bFatollahzadeh et al, 2016;Magalhães-Junior et al, 2016;Maia et al, 2010Maia et al, , 2008Martín-Sánchez et al, 2007;Mendonça et al, 2017;Millán et al, 2011;Otranto et al, 2017;Pennisi et al, 2000Pennisi et al, , 1998Sarkari et al, 2009;Spada et al, 2013;Vita et al, 2005). Prospective studies may confirm that cats play an epidemiological role as additional reservoir species of L. infantum as it was well established for dogs .…”
Section: Prevention Of L Infantum Infectionmentioning
confidence: 99%
“…In previous studies, the DPP ® test showed specificity ranging from 87.8% to 98.6% and sensitivity between 90.6% and 98% using confirmed positive samples 9,10 . However, despite showing high levels of sensitivity among clinically symptomatic dogs, sensitivity of the DPP ® test to identify the Leishmania infection in asymptomatic dogs was only 47% in one of the studies 13 .…”
Section: Discussionmentioning
confidence: 85%
“…The SNAP ® Canine Leishmania Antibody Test was designed to diagnose infections by L. infantum. It was evaluated in a large population of dogs, including 283 dogs positive for CVL attributed to L. chagasi, 86 clinically healthy dogs from a non-endemic area, and 31 dogs infected with other infectious and parasitic agents, to determine whether the infection by L. chagasi would also be identified by this test 10 . The sensitivity of the SNAP ® test was 94.7% and the specificity was 90.6% in that study.…”
Section: Discussionmentioning
confidence: 99%
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