140 Years of the Leçons sur l’histologie du système nerveux: the pioneering description of the nodes of Ranvier

Abstract

This paper reviews aspects of the life and work of Professor Louis Ranvier 140 years after the publication of Leçons sur l’histologie du système nerveux, published in 1878, and shows the importance of the histological description of myelinated fibers of the nodes of Ranvier.

The concept of tissue regeneration: Epistemological and historical enquiry from early ideas on the regeneration of bone to the microscopic observations of the regeneration of peripheral nerves

“…Following Waller’s studies on degeneration, Ranvier added many microscopic details which he mentioned in his Leçons sur l’histologie du système nerveux ( Hernandez Fustes et al, 2019 ), including the “progressive alterations of the nerve tubes” of the distal stump of a nerve cut in a frog or a rabbit, with “myelin segmentation”, “fatty granules” merging into numerous droplets more abundant in the medial part of the section, but which were partly in agreement with Nasse (1839, p . 409–413).…”