2013
DOI: 10.1590/0004-282x20130057
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Abstract: Vascular mild cognitive impairment (VaMCI) represents an early symptomatic stage of vascular cognitive impairment and might be associated to fronto-executive dysfunction.MethodsTwenty-six individuals (age: 73.11±7.90 years; 65.4% female; schooling: 9.84±3.61 years) were selected through neuropsychological assessment and neuroimaging. Clinical and neuroimaging data of VaMCI individuals (n=15) were compared to normal controls (NC, n=11) and correlated with Fazekas scale.ResultsVaMCI performed significantly worse… Show more

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Cited by 30 publications
(32 citation statements)
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“…The MCI groups differed significantly on four test variables in CAB, covering the cognitive domains memory, language and executive functions, which means that the hypothesis was fulfilled only partly – there was no significant difference on the speed/attention test in CAB. Overall, the MCI‐vas group consistently tended to perform worse than the MCI‐nov group, which confirms the findings of other recent reports .…”
Section: Discussionsupporting
confidence: 90%
See 1 more Smart Citation
“…The MCI groups differed significantly on four test variables in CAB, covering the cognitive domains memory, language and executive functions, which means that the hypothesis was fulfilled only partly – there was no significant difference on the speed/attention test in CAB. Overall, the MCI‐vas group consistently tended to perform worse than the MCI‐nov group, which confirms the findings of other recent reports .…”
Section: Discussionsupporting
confidence: 90%
“…Consequently, patients with vascular disease can develop symptoms over time and be diagnosed with MCI, not unlike patients with a degenerative pathology . Lately the contribution of vascular disease to MCI has been paid increasing attention in clinical as well as population‐based studies .…”
Section: Introductionmentioning
confidence: 99%
“…The distinctive neuropsychological characteristics found in early stage PD-MCI are caused by executive function damage due to prefrontal hypofunction or malfunction [9]. However, it is difficult to distinguish PD-MCI from MCI or vascular-MCI, because they show similar symptoms [10]. Additionally, people with PD experience a slowly deteriorating cognitive deficit and impaired motor function, which can be mistaken for cognitive frailty as part of the normal aging process.…”
Section: Introductionmentioning
confidence: 99%
“…Nevertheless, it can be difficult to determine the clinical extent and relevance of white matter lesions in SIVCI particularly as their full extent may not be visible on diagnostic CT/MRI scans. In the research domain, a significant body of evidence supports a strong association between pathological brain changes, including distributed or global structural and functional breakdown in white matter, and cognitive decline [5][6][7][8][9][10][11][12][13], particularly behavioral reaction time (RT) [6][7][8][9][10][14][15][16][17][18][19][20][21][22][23][24][25]. Testing RT may therefore be an important adjunct to the diagnosis of SIVCI and the determination of disease load that may not be fully represented by the level of periventricular white matter visible on diagnostic scans.…”
Section: Introductionmentioning
confidence: 99%