Abstract:Background: Clinical and imaging are required to characterize activity and progression in MS. The parameters for activity are well defined but not those for progression. The ideal aim for long-term treatment is that neither clinical nor imaging signs of disease should be present, and also no brain atrophy. Objectives: To conduct a comparative clinical-imaging study focusing on MRI brain volumetry. Methods: 174 consecutive relapsing-remitting MS patients (McDonald 2001) were studied, focusing on activity a… Show more
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