2014
DOI: 10.1590/0004-2730000003209
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Abstract: Objective: The aim of this study was to investigate UBASH3A gene variation association with autoimmune thyroid disease and clinical features in a Chinese Han population. Subjects and methods: A total of 667 AITD patients (417 GD and 250 HT) and 301 healthy controls were genotyped for two single nucleotide polymorphisms (SNPs) rs11203203, rs3788013 of UBASH3A gene, utilizing the Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometer (MALDI-TOF-MS) Platform. Results: Between the control gro… Show more

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Cited by 5 publications
(1 citation statement)
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“…Meanwhile, oxidative stress occurs by the imbalance between prooxidants and antioxidants, which causes damage to macromolecules, disruption of ions in redox signaling, and alterations of proteins [9]. Many studies found an association between increased oxidative stress and HT [10]. Though, the exact link between them is still debated [11].…”
Section: Introductionmentioning
confidence: 99%
“…Meanwhile, oxidative stress occurs by the imbalance between prooxidants and antioxidants, which causes damage to macromolecules, disruption of ions in redox signaling, and alterations of proteins [9]. Many studies found an association between increased oxidative stress and HT [10]. Though, the exact link between them is still debated [11].…”
Section: Introductionmentioning
confidence: 99%