Determination of antimicrobial and antioxidant potential of agro-waste peels

Naqvi, Syeda Andleeb Zahra; Irfan, Ali; Zahoor, Ameer Fawad; Zafar, Muhammad; Maria, Anum; Chand, Amar J; Ashfaq, Shomaila

doi:10.1590/0001-3765202020181103

Cited by 8 publications

(4 citation statements)

References 15 publications

(9 reference statements)

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“…The multimethodological approach afforded a detailed fingerprint of the considered wastes allowing us to hypothesize their reuse in different applications. The presence of amino acids, polyphenols, organic acids, organosulphur compounds, lipids, and so on suggests potential employment in the cosmetic, pharmaceutic, and food supplements industries [ 45 , 46 ].…”

Section: Discussionmentioning

confidence: 99%

Characterization and Valorization of ‘Sulmona Red Garlic’ Peels and Small Bulbs

et al. 2022

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‘Sulmona red garlic’ is an Italian variety characterized by a red tunica surrounding a white bulb. Red tunicae and non-commercial small bulbs are food wastes that must be studied for their added value. Hydroalcoholic extracts, obtained by separated inner and outer tunicae and peeled bulbs of small commercial ‘Sulmona red garlic’ bulbs, harvested at two different years, were first characterized with respect to their color, polyphenolic content, and antiradical activity. Then, an untargeted metabolic profile by means of electrospray ionization Fourier transform ion cyclotron resonance (ESI FT-ICR) mass spectrometry led to a comparative evaluation of the chemical diversity of six different samples. The study was completed by biological tests aiming to evaluate the associated health potential. Data on monocytes/macrophages showed good biocompatibility and a promising cytoprotective effect under oxidative stress conditions of all the extracts. At a molecular level, all the garlic extracts were able to downregulate the hydrogen peroxide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression through the modulation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-ĸB) and peroxynitrite intracellular amounts, at different extents depending on the extract, the cell type, and the concentration. On the whole, data highlight an associated health potential of the extracts of this waste plant material both in terms of cytoprotection and of anti-inflammatory activity.

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Section: Discussionmentioning

confidence: 99%

Characterization and Valorization of ‘Sulmona Red Garlic’ Peels and Small Bulbs

et al. 2022

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“…In our previous studies, , we found that ginger peel contains various types of chemical components, many of which can significantly reduce the rate of apoptosis and increase survival of normal human lung bronchial epithelial cells . In addition, other efforts have shown that ginger peel has antibiotic activity, its extracts effectively inhibited different pathogenic bacterial and fungal strains …”

Section: Introductionmentioning

confidence: 98%

“…14 In addition, other efforts have shown that ginger peel has antibiotic activity, its extracts effectively inhibited different pathogenic bacterial and fungal strains. 15 Ginger extract and its polyphenolic compounds, including 6-Gi, 8-Gi, 10-Gi, 6-shogaol, and 10-dehydrogingerdione, have been used as antioxidants and anti-inflammatory agents in the clinic for a long time. 16 The polyphenol constituents in ginger play a protective roles against fibrosis by reducing inflammation, the degree of kidney damage, 17,18 nephrotoxicity induced by cisplatin, and renal fibrosis.…”

Section: ■ Introductionmentioning

confidence: 99%

Renoprotective Glycoside Derivatives from Zingiber officinale (Ginger) Peels

Song,

Fang,

Zhang

et al. 2023

J. Agric. Food Chem.

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As a widely consumed spice and traditional Chinese medicine, Zingiber officinale Roscoe (ginger) has been used in the treatment of nausea, coughs, and colds. In this article, 18 new glycosides (1–18) and six known analogues (19–24) were isolated from the peel of ginger. The planar structures of these compounds were determined by using HR-ESI-MS and extensive spectroscopic techniques (UV, IR, 1D-NMR, and 2D-NMR). Their relative and absolute configurations of the stereogenic centers in the new natural products were determined by analysis of NMR data, using a quantum mechanical NMR approach and time-dependent density functional theory based electronic circular dichroism calculations. The renal fibrosis activities of the isolated natural products together with those of 6-gingerol (6-Gi), 8-gingerol (8-Gi), and 10-gingerol (10-Gi) were evaluated in TGF-β1 induced NRK-52E cells. Compounds 9, 10, 15, 22–24, 6-Gi, 8-Gi, and 10-Gi were found to be active toward extracellular matrix, indicating that they have potential renal fibrosis activities.

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“…It is generally discarded and has been seldomly studied so far [ 7 ]. This by-product has been used to obtain extracts and evaluate their antimicrobial [ 8 , 9 ] and antioxidant capacities [ 10 , 11 ], or to improve the antimicrobial activity of edible films and coatings [ 7 , 12 , 13 , 14 ]. However, to the best of the author’s knowledge, garlic peel extracts against fungal phytopathogens, such as Colletotrichum gloeosporioides and Botrytis cinerea in in vivo and in vitro assays, have not been evaluated yet.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Pretreatments and Extraction Conditions on the Antifungal and Antioxidant Effects of Garlic (Allium sativum) Peel Extracts

Carreón‐Delgado

Hernández‐Montesinos

Rivera-Hernández

et al. 2023

Plants

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This study aimed to evaluate the effect of pretreatments and extraction conditions on the antioxidant and antifungal characteristics of garlic peel extracts. The effect of pretreatments (fermentation and steam cooking) on the yield, antifungal (Colletotrichum gloeosporioides and Botrytis cinerea), and antioxidant (total phenolic compounds, total flavonoids, and antioxidant capacity) properties of garlic peel extracts were evaluated. A selected pretreatment was applied to evaluate the extraction conditions (solvent, solvent concentration, temperature, and time) on the antifungal activity of garlic peel extracts. At last, garlic peel extracts obtained under specific conditions was applied to papaya and strawberry fruits as preventive and curative treatments against Colletotrichum gloeosporioides and Botrytis cinerea, respectively. Steam cooking pretreatment significantly increased the antifungal and antioxidant capacities of garlic peel extracts compared to the fermentation process. Garlic peel extracts obtained with methanol (60%) for 18 h (25 °C) showed the highest antifungal activity against both microorganisms assessed (57.57% and 75.76% for B. cinerea and C. gloeosporioides, respectively,) on in vitro assays. Moreover, in vivo results indicated that preventive treatment significantly reduced rot disease in papaya (88.95%) and strawberry (54.13%) fruits. Although more studies about the antifungal mechanisms of garlic peel extracts are needed, these results indicated that garlic peel extracts could be used as an antifungal agent.

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Determination of antimicrobial and antioxidant potential of agro-waste peels

Cited by 8 publications

References 15 publications

Characterization and Valorization of ‘Sulmona Red Garlic’ Peels and Small Bulbs

Characterization and Valorization of ‘Sulmona Red Garlic’ Peels and Small Bulbs

Renoprotective Glycoside Derivatives from Zingiber officinale (Ginger) Peels

Evaluation of Pretreatments and Extraction Conditions on the Antifungal and Antioxidant Effects of Garlic (Allium sativum) Peel Extracts

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