2016
DOI: 10.1590/0001-3765201620150776
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Considering that Alzheimer's disease is a prevalent neurodegenerative disease worldwide, we investigated the activities of three key kinases: creatine kinase, pyruvate kinase and adenylate kinase in the hippocampus and cerebral cortex in Alzheimer's disease model. Male adult Swiss mice received amyloid-β or saline. One day after, mice were treated with blank nanocapsules (17 ml/kg) or meloxicam-loaded nanocapsules (5 mg/kg) or free meloxicam (5 mg/kg). Treatments were performed on alternating days, until the e… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
1
0

Year Published

2018
2018
2023
2023

Publication Types

Select...
5

Relationship

0
5

Authors

Journals

citations
Cited by 5 publications
(1 citation statement)
references
References 59 publications
(67 reference statements)
0
1
0
Order By: Relevance
“…[9] Another study revealed that oxidation of CK in AD led to the disruption of CSF AD pathology proteins and that AD patients' brains exhibited decreased CK activity. [10] As there are no clear serological markers for the diagnosis and prognosis of cognitive impairment, peripheral CK levels can be considered a non-invasive method and a serological marker for diagnosing cardiovascular diseases and cognitive impairment. However, this needs to be further demonstrated in future research.…”
mentioning
confidence: 99%
“…[9] Another study revealed that oxidation of CK in AD led to the disruption of CSF AD pathology proteins and that AD patients' brains exhibited decreased CK activity. [10] As there are no clear serological markers for the diagnosis and prognosis of cognitive impairment, peripheral CK levels can be considered a non-invasive method and a serological marker for diagnosing cardiovascular diseases and cognitive impairment. However, this needs to be further demonstrated in future research.…”
mentioning
confidence: 99%