2013
DOI: 10.1590/0001-3765201393812
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Abstract: Casearia sylvestris Swartz (Salicaceae) has been used in traditional medicine and its leaf extracts have been exhibited important pharmacological activities. The species presents morphological, chemical and genetic variation. Two varieties are considered due external morphological differences: C. sylvestris var. sylvestris and var. lingua. There are difficulties in definition of these varieties. The objective of this work is to evaluate chemical and morpho-anatomical differences between C. sylvestris varieties… Show more

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Cited by 12 publications
(9 citation statements)
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“…The results obtained in this study indicate that certain extracts and fractions of C. sylvestris exhibit potent antimicrobial and antibiofilm effects against two of the main microorganisms related to the pathogenesis of dental caries. Previous studies that performed systematic screenings of C. sylvestris demonstrated a varied phytochemical composition for leaf extracts [32, 33]. This varied phytochemical composition (presence of clerodan diterpenes and glycosylated flavonoids) provides a rich source of molecules that may exhibit cariostatic properties, and their potential must be explored.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The results obtained in this study indicate that certain extracts and fractions of C. sylvestris exhibit potent antimicrobial and antibiofilm effects against two of the main microorganisms related to the pathogenesis of dental caries. Previous studies that performed systematic screenings of C. sylvestris demonstrated a varied phytochemical composition for leaf extracts [32, 33]. This varied phytochemical composition (presence of clerodan diterpenes and glycosylated flavonoids) provides a rich source of molecules that may exhibit cariostatic properties, and their potential must be explored.…”
Section: Discussionmentioning
confidence: 99%
“…sylvestris (from Atlantic Forest) presents a rich phytochemical composition, with abundant diterpenes, considered taxonomic markers for this genus [31] while phenolic compounds (flavonoids) predominate in var. lingua [32, 33].…”
Section: Introductionmentioning
confidence: 99%
“…Clerodane diterpenes were identified at Núcleo de Bioensaios, Biossíntese e Ecofisiologia de Produtos Naturais (NuBBE), Institute of Chemistry, UNESP (Araraquara, São Paulo, Brazil) using high performance liquid chromatography (HPLC-DAD) as described in Claudino et al (2013) and nuclear magnetic resonance considering literature data (Itokawa et al 1990. These analyses showed FC presents 56.5% (mg/g) of the total casearins, with caseargrewiin F and casearin X being the most present molecules (9.9 and 14.2%, respectively) (Ferreira et al 2014).…”
Section: Extraction Of the Fraction With Casearins (Fc)mentioning
confidence: 99%
“…lingua , which is typical of warm and dry habitats (e. g., Cerrado). Intermediate specimens between the two Casearia sylvestris Sw. varieties have also been described [2–4] . C. sylvestris has been studied since 1939.…”
Section: Introductionmentioning
confidence: 99%