volume 9, issue 2, Pe88525 2014
DOI: 10.1371/journal.pone.0088525
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Pierluigi Gasparini, Matteo Fassan, Luciano Cascione, Gulnur Guler, Serdar Balci, Cigdem Irkkan, Carolyn Paisie, Francesca Lovat, Carl Morrison, Jianying Zhang, Aldo Scarpa, Carlo M. Croce, Charles L. Shapiro, Kay Huebner et al.

Abstract: Triple negative breast cancers are a heterogeneous group of tumors characterized by poor patient survival and lack of targeted therapeutics. Androgen receptor has been associated with triple negative breast cancer pathogenesis, but its role in the different subtypes has not been clearly defined. We examined androgen receptor protein expression by immunohistochemical analysis in 678 breast cancers, including 396 triple negative cancers. Fifty matched lymph node metastases were also examined. Association of expr…

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