2017
DOI: 10.1186/s13054-017-1657-6
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Abstract: BackgroundCritical illness is associated with increased risk of fragility fracture and loss of bone mineral density (BMD), although the impact of medication exposures (bone anti-fracture therapy or glucocorticoids) and time remain unexplored. The objective of this study was to describe the association of time after ICU admission, and post-ICU administration of bone anti-fracture therapy or glucocorticoids after critical illness, with change in BMD.MethodsIn this prospective observational study, conducted in a … Show more

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Cited by 25 publications
(28 citation statements)
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References 37 publications
(35 reference statements)
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“…First, this study showed that BMD significantly decreased after intensive care, especially in the non‐osteoporosis groups. This finding is similar to a previous report by Orford et al . who found that BMD decreased in the 2 years after critical care.…”
Section: Discussionsupporting
confidence: 93%
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“…First, this study showed that BMD significantly decreased after intensive care, especially in the non‐osteoporosis groups. This finding is similar to a previous report by Orford et al . who found that BMD decreased in the 2 years after critical care.…”
Section: Discussionsupporting
confidence: 93%
“…Loss of BMD after critical care has been reported in previous studies . One study showed that patients with acute respiratory distress syndrome had a decreased BMD after 10 days.…”
Section: Discussionmentioning
confidence: 63%
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