2011
DOI: 10.1177/1358863x11398519
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Abstract: Acrocyanosis is symmetric, painless, discoloration of different shades of blue in the distal parts of the body that is marked by symmetry, relative persistence of the skin color changes with aggravation by cold exposure, and frequent association with local hyperhidrosis of hands and feet. Described over a century ago and despite seeming familiarity, it remains a poorly understood condition that shares much in clinical presentation with other conditions characterized by skin color changes in the distal parts of… Show more

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Cited by 59 publications
(56 citation statements)
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“…Acrocyanosis is a rare disorder characterized by cyanotic changes and coldness most commonly of the hands but also occurring in the feet and distal parts of the face. The exact pathophysiologic mechanism is unknown, but is suspected to relate to vasospasm of the peripheral arterioles, with compensatory dilatation of the post capillary venules . This is generally believed to be mainly a cosmetic problem, not associate with significant discomfort or risk for tissue damage.…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…Acrocyanosis is a rare disorder characterized by cyanotic changes and coldness most commonly of the hands but also occurring in the feet and distal parts of the face. The exact pathophysiologic mechanism is unknown, but is suspected to relate to vasospasm of the peripheral arterioles, with compensatory dilatation of the post capillary venules . This is generally believed to be mainly a cosmetic problem, not associate with significant discomfort or risk for tissue damage.…”
Section: Methodsmentioning
confidence: 99%
“…The exact pathophysiologic mechanism is unknown, but is suspected to relate to vasospasm of the peripheral arterioles, with compensatory dilatation of the post capillary venules. 73 This is generally believed to be mainly a cosmetic problem, not associate with significant discomfort or risk for tissue damage. The cyanotic features are often most prominent in the cold and general resolve with warming of the skin.…”
Section: Peripheral Vascular Abnormalitiesmentioning
confidence: 99%
“…The correlation between imaging evidence of LRV compression and clinical symptoms is strenuous; thus, interventions should be proposed only when symptoms are severe or persistent. 6 Medical, surgical, and endovascular means have all been previously employed in managing PCS. Medical management comprises hormone analogues and analgesics, surgical treatment involves ligation of ovarian veins, hysterectomy with or without bilateral salpingo-oophorectomy, and endovascular treatment involves transcatheter embolization.…”
Section: Discussionmentioning
confidence: 99%
“…When PCS is secondary to NCS, occlusion of the collateral veins may increase renocaval pressure gradients; therefore, measures to relieve the renocaval pressure gradients should also be undertaken. 6 Management of NCS could be endovascular ( intravascular balloon angioplasty and stenting using self-expanding stent, balloon expandable stent, or self-expanding covered stents) or surgical (medial nephropexy with excision of renal varicosities, LRV bypass, LRV transposition with or without Dacron wedge insertion between SMA and aorta, SMA transposition, renal-to-IVC shunt, renal autotransplant, gonadocaval bypass, external stenting, and nephrectomy).…”
Section: Discussionmentioning
confidence: 99%
“…Of note, RP may occur concomitantly with acrocyanosis. In addition, the persistence of acrocyanosis is also relative, and it may also demonstrate improvement in the summer as well as in horizontal and elevated position of the hand vs. dependent position [72].…”
Section: Differential Diagnosis Of Rp With Other Vascular Acrosyndromesmentioning
confidence: 99%