Problem Drinking and Depression in Older Adults with Multiple Chronic Health Conditions

Mowbray, Orion; Washington, Tiffany; Purser, Greg; O'Shields, Jay

doi:10.1111/jgs.14479

Cited by 6 publications

(3 citation statements)

References 44 publications

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“…The high prevalence of depression has been corroborated by a recent meta-analysis, where 30% of T2DM patients reported depression [ 41 ]. In particular, elderly patients suffering from depression and alcohol misuse have worse health outcomes, poorer physical and mental health, and a higher mortality rate [ 42 ]. Alcohol abuse can also result in unsatisfactory patient control of diabetes and hypertension [ 42 ].…”

Section: Discussionmentioning

confidence: 99%

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Alcohol Consumption in Diabetic Patients with Nonalcoholic Fatty Liver Disease

Patel

Smith

Connor

et al. 2017

Canadian Journal of Gastroenterology and Hepatology

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Aim To examine the association between lifetime alcohol consumption and significant liver disease in type 2 diabetic patients with NAFLD. Methods A cross-sectional study assessing 151 patients with NAFLD at risk of clinically significant liver disease. NAFLD fibrosis severity was classified by transient elastography; liver stiffness measurements ≥8.2 kPa defined significant fibrosis. Lifetime drinking history classified patients into nondrinkers, light drinkers (always ≤20 g/day), and moderate drinkers (any period with intake >20 g/day). Result Compared with lifetime nondrinkers, light and moderate drinkers were more likely to be male (p = 0.008) and to be Caucasian (p = 0.007) and to have a history of cigarette smoking (p = 0.000), obstructive sleep apnea (p = 0.003), and self-reported depression (p = 0.003). Moderate drinkers required ≥3 hypoglycemic agents to maintain diabetic control (p = 0.041) and fibrate medication to lower blood triglyceride levels (p = 0.044). Compared to lifetime nondrinkers, light drinkers had 1.79 (95% CI: 0.67–4.82; p = 0.247) and moderate drinkers had 0.91 (95% CI: 0.27–3.10; p = 0.881) times the odds of having liver stiffness measurements ≥8.2 kPa (adjusted for age, gender, and body mass index). Conclusions In diabetic patients with NAFLD, light or moderate lifetime alcohol consumption was not significantly associated with liver fibrosis. The impact of lifetime alcohol intake on fibrosis progression and diabetic comorbidities, in particular obstructive sleep apnea and hypertriglyceridemia, requires further investigation.

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Section: Discussionmentioning

confidence: 99%

“…In particular, elderly patients suffering from depression and alcohol misuse have worse health outcomes, poorer physical and mental health, and a higher mortality rate [ 42 ]. Alcohol abuse can also result in unsatisfactory patient control of diabetes and hypertension [ 42 ].…”

Section: Discussionmentioning

confidence: 99%

Alcohol Consumption in Diabetic Patients with Nonalcoholic Fatty Liver Disease

Patel

Smith

Connor

et al. 2017

Canadian Journal of Gastroenterology and Hepatology

View full text Add to dashboard Cite

show abstract

“…However, alcohol use has been found to increase the risk of hospitalization among adults [88]. Those with alcohol-use and multiple chronic health conditions are more likely to report depressive symptoms than are adults of a similar age who do not have alcohol-use disorder [89].…”

Section: Am J Biomed Sci and Resmentioning

confidence: 99%