The antioxidant properties of the chestnut bee pollen extract and its preventive action against oxidatively induced damage in DNA bases

Şahin, Saliha; Karkar, Büşra

doi:10.1111/jfbc.12888

Cited by 12 publications

(5 citation statements)

References 31 publications

(60 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, the determination of the phenolic profile of bee pollen is considered the first step toward the standardization and prediction of the usefulness of this beehive product. The analysis of their composition revealed that the polyphenolic content presented an average of 3% to 5% of their composition, depending on the botanical origin of the bee pollen [ 133 ].…”

Section: Chemical Compositionmentioning

confidence: 99%

Bee Pollen as Functional Food: Insights into Its Composition and Therapeutic Properties

et al. 2023

View full text Add to dashboard Cite

Bee pollen is a hive product made up of flower pollen grains, nectar, and bee salivary secretions that beekeepers can collect without damaging the hive. Bee pollen, also called bee-collected pollen, contains a wide range of nutritious elements, including proteins, carbs, lipids, and dietary fibers, as well as bioactive micronutrients including vitamins, minerals, phenolic, and volatile compounds. Because of this composition of high quality, this product has been gaining prominence as a functional food, and studies have been conducted to show and establish its therapeutic potential for medical and food applications. In this context, this work aimed to provide a meticulous summary of the most relevant data about bee pollen, its composition—especially the phenolic compounds—and its biological and/or therapeutic properties as well as the involved molecular pathways.

show abstract

Section: Chemical Compositionmentioning

confidence: 99%

Bee Pollen as Functional Food: Insights into Its Composition and Therapeutic Properties

et al. 2023

View full text Add to dashboard Cite

show abstract

“…Although the SBP had only a significant antityrosinase activity, this was at least in part due to the safflospermidine A and B content. However, an antioxidant activity was previously found in the bee pollen from chestnuts, roses, and Schisandra chinensis (Sahin and Karkar, 2019;Yang et al, 2019;Shen et al, 2019). Thus, identification of the plant origin of bee pollen is necessary in order to get the targeted bioactivity.…”

Section: Discussionmentioning

confidence: 99%

Safflospermidines from the bee pollen of Helianthus annuus L. exhibit a higher in vitro antityrosinase activity than kojic acid

Khongkarat

Ramadhan

Phuwapraisirisan

et al. 2020

Heliyon

View full text Add to dashboard Cite

Background: Ozone deterioration in the atmosphere has become a severe problem causing overexposure of ultraviolet light, which results in humans in melanin overproduction and can lead to many diseases, such as skin cancer and melasma, as well as undesirable esthetic appearances, such as freckles and hyperpigmentation. Although many compounds inhibit melanin overproduction, some of them are cytotoxic, unstable, and can cause skin irritation. Thus, searching for new natural compounds with antityrosinase activity and less/no side effects is still required. Here, bee pollen derived from sunflower (Helianthus annuus L.) was evaluated. Materials and methods: Sunflower bee pollen (SBP) was collected from Apis mellifera bees in Lopburi province, Thailand in 2017, extracted by methanol and sequentially partitioned with hexane and dichloromethane (DCM). The in vitro antityrosinase activity was evaluated using mushroom tyrosinase and the half maximal inhibitory concentration (IC 50 ) is reported. The antioxidation activity was determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay and reported as the half maximal effective concentration. Two pure compounds with antityrosinase activity were isolated by silica gel 60 column chromatography (SG 60 CC) and high performance liquid chromatography (HPLC), and their chemical structure deduced by Nuclear Magnetic Resonance (NMR) analysis. Results:The DCM partitioned extract of SBP (DCMSBP) had an antityrosinase activity (IC 50 , 159.4 μg/mL) and was fractionated by SG 60 CC, providing five fractions (DCMSBP1-5). The DCMSBP5 fraction was the most active (IC 50 ¼ 18.8 μg/mL) and further fractionation by HPLC gave two active fractions, revealed by NMR analysis to be safflospermidine A and B. Interestingly, both safflospermidine A and B had a higher antityrosinase activity (IC 50 of 13.8 and 31.8 μM, respectively) than kojic acid (IC 50 of 44.0 μM). However, fraction DCMSBP5 had no significant antioxidation activity, while fractions DCMSBP1-4 showed a lower antioxidation activity than ascorbic acid. Conclusion: Safflospermidine A and B are potential natural tyrosinase inhibitors.

show abstract

“…A literature review revealed previous reports on the use of a chemical system to evaluate the antioxidant capacity of pollen extracts (Ozkan et al, 2017;Qiu et al, 2017;Saliha & Büşra, 2019). Dong, Zhang, Li, and Ren (2010) studied the in vitro antioxi-dant capacity of eight different pollen alcohol extracts and found that the DPPH radical scavenging capacity, total reducing power, and TAC were in the order of canola> rose> buckwheat; the hydroxyl radical scavenging capacity was in the order of canola> buckwheat> rose.…”

Section: Chemically Determined Antioxidant Effects Of Cfpsmentioning

confidence: 99%

Chemical and cytological evaluation of honeybee pollen antioxidant ability

Yang

Liu

Wang

et al. 2020

Journal of Food Science

View full text Add to dashboard Cite

The crude flavonoid extract of pollen (CFP) of four species of honeybee pollens were extracted with ethanol, and the total flavonoid contents ranged from 3.4 to 14.5 mg rutin/g dry weight. The antioxidant activities of the CFPs were evaluated from both chemical and cytological aspects. Comprehensive antioxidant scores were determined based on these two evaluation systems. The results showed that canola CFP had the highest antioxidant capacity among the four CFPs. A cytotoxicity assay was conducted to assess the safety threshold of the CFPs, and canola CFP was proved to be the least toxic to vascular endothelial cell. Of the four tested CFPs, this research suggests that canola CFP is the most promising natural antioxidant. In addition, high‐performance liquid chromatography (HPLC) analysis detected seven flavonoid glycosides in the hydrolysates of the four CFPs. Among them, quercetin and kaempferol were present in all four honeybee pollen extracts, but there were significant differences between their contents. A correlation analysis revealed a strong correlation between the content of quercetin in the pollen extract and the extract's antioxidant activity. Practical Application Many varieties of honeybee pollen are commercially available. The results of this study help guide consumers to choose honeybee pollens that have a better antioxidant effect. This report can also provide guidance and data in support of the development of honeybee pollen health products.

show abstract

The antioxidant properties of the chestnut bee pollen extract and its preventive action against oxidatively induced damage in DNA bases

Cited by 12 publications

References 31 publications

Bee Pollen as Functional Food: Insights into Its Composition and Therapeutic Properties

Bee Pollen as Functional Food: Insights into Its Composition and Therapeutic Properties

Safflospermidines from the bee pollen of Helianthus annuus L. exhibit a higher in vitro antityrosinase activity than kojic acid

Chemical and cytological evaluation of honeybee pollen antioxidant ability

Contact Info

Product

Resources

About