Re: "Should Meta-Analyses of Interventions Include Observational Studies in Addition to Randomized Controlled Trials? A Critical Examination of Underlying Principles"

Shrier, Ian; Boivin, Jean‐François; Steele, Russell; Platt, Robert W.; Furlan, Andrea D; Kakuma, Ritsuko; Brophy, James M.; Rossignol, Michel

doi:10.1093/aje/kwp016

Cited by 111 publications

(1 citation statement)

References 1 publication

(1 reference statement)

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“…. We call the attention of the reader to the subtle difference between probability and confidence, as presented in [4], which justifies the use of distinct terminology. To clarify, before the observations are obtained and by using the order statistics (minimum and maximum), we write the following expression:…”

Section: Confidence Intervals For Mediansmentioning

confidence: 99%

Using Confidence Statements to Ordering Medians: A Simple Microarray Nonparametric Analysis

Pereira¹,

Polpo²

2020

OJS

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Comparing two samples about corresponding parameters of their respective populations is an old and classical statistical problem. In this paper, we present a simple yet effective tool to compare two samples through their medians. We calculate the confidence of the statement "the median of the first population is strictly smaller (larger) than the median of the second." We analyze two real data sets and empirically demonstrate the quality of the confidence for such a statement. This confidence in the order of the medians is to be seen as a pre-analysis tool that can provide useful insights for comparing two or more populations. The method is entirely based on their exact distribution with no need for asymptotic considerations. We also provide the Quor statistical software, an R package that implements the ideas discussed in this work.

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Section: Confidence Intervals For Mediansmentioning

confidence: 99%

Using Confidence Statements to Ordering Medians: A Simple Microarray Nonparametric Analysis

Pereira¹,

Polpo²

2020

OJS

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Immediate and Sustained Outcomes and Moderators Associated With Metacognitive Training for Psychosis

et al. 2022

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Key Points Question What are the immediate and sustained outcomes associated with metacognitive training (MCT) for psychosis, and are there specific treatment- or participant-related moderators of associations? Findings This systematic review and meta-analysis of 43 studies (40 reports synthesized in meta-analysis, N=1816; 6 reports included in narrative review) on individuals with schizophrenia spectrum and related psychotic disorders found MCT was associated with reduced delusions, hallucinations, and cognitive biases. Metacognitive training was also associated with reduced negative symptoms and improved self-esteem and functioning. Meaning The findings of this study suggest that MCT is an accessible evidence-based intervention, deliverable by a variety of mental health care professionals, and appears to be ready for large-scale implementation; MCT may merit inclusion in clinical guideline recommendations for the treatment of individuals with schizophrenia.

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Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain in adults and children

Weinstein

Levene

Cohen

et al. 2018

Cochrane Database of Systematic Reviews

110

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We conclude that there is moderate-quality evidence that regional anaesthesia may reduce the risk of developing PPP after three to 18 months after thoracotomy and three to 12 months after caesarean section. There is low-quality evidence that regional anaesthesia may reduce the risk of developing PPP three to 12 months after breast cancer surgery. There is moderate evidence that intravenous infusion of local anaesthetics may reduce the risk of developing PPP three to six months after breast cancer surgery.Our conclusions are considerably weakened by the small size and number of studies, by performance bias, null bias, attrition and missing data. Larger, high-quality studies, including children, are needed. We caution that except for breast surgery, our evidence synthesis is based on only a few small studies. On a cautionary note, we cannot extend our conclusions to other surgical interventions or regional anaesthesia techniques, for example we cannot conclude that paravertebral block reduces the risk of PPP after thoracotomy. There are seven ongoing studies and 12 studies awaiting classification that may change the conclusions of the current review once they are published and incorporated.

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Re: "Should Meta-Analyses of Interventions Include Observational Studies in Addition to Randomized Controlled Trials? A Critical Examination of Underlying Principles"

Cited by 111 publications

References 1 publication

Using Confidence Statements to Ordering Medians: A Simple Microarray Nonparametric Analysis

Using Confidence Statements to Ordering Medians: A Simple Microarray Nonparametric Analysis

Immediate and Sustained Outcomes and Moderators Associated With Metacognitive Training for Psychosis

Local anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain in adults and children

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