2003
DOI: 10.1079/pns2003275
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Abstract: Epidemiological evidence suggests that diets rich in fruit and vegetables decrease the risk of premature mortality from major clinical conditions, including cancer and heart disease. However, it is not yet clear which components or combination of components in fruit and vegetables are protective and what is their mechanism of action. Such scientific uncertainty does not seem to inhibit the marketing of a huge range of plant-based concoctions, promoted as ‘magic bullets’ for optimum health. For example, the pur… Show more

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Cited by 239 publications
(120 citation statements)
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“…However, even when good experimental evidence exists, results need to be interpreted with caution in relation to human health benefits, as polyphenols may have limited bioavailability and may also be extensively metabolised (12).…”
Section: Resultsmentioning
confidence: 99%
“…However, even when good experimental evidence exists, results need to be interpreted with caution in relation to human health benefits, as polyphenols may have limited bioavailability and may also be extensively metabolised (12).…”
Section: Resultsmentioning
confidence: 99%
“…Based 217 upon our previous experience in flavonoid apigenin [26] and lignan analysis [9][10]27] those potential metabolites in this moment. Although SDG and/or its metabolites were not 225 detectable in the treated cells, it should be noted that it was not expected for intact SDG to be 226 absorbed, since a phytochemical glycoside is usually deglycosilation by β-glucosidase or lactase 227 phlorozin hydrolase [28]. Therefore, SDG-treated cells with undetectable intracellular SDG or its 228 currently known metabolites observed in this study may provide novel insight into SDG 229 metabolism and bioavailability if exposed directly to the colonic cells before degradation by 230 microorganisms in human gut.…”
Section: Page 12 Of 23mentioning
confidence: 99%
“…Approximately, 8000 flavonoids have been characterized and the major classes are flavones (apigenin, luteolin), flavonols (quercetin, kaempferol), flavanones (hesperetin, naringenin), flavanols (epigallocatechin, EGCG), anthocyanins (cyanidnin, delphinidin) and isoflavones (genistein, daidzein) (Duthie et al 2003).…”
Section: Introductionmentioning
confidence: 99%